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遏制埃塞俄比亚索马里地区多洛区循环疫苗衍生脊髓灰质炎 2 型的爆发:应对疫情爆发。

Curbing an outbreak of circulating vaccine derived poliovirus type 2 in Dollo Zone, Somali Region, Ethiopia: response to outbreak.

机构信息

CORE Group Polio Project Secretariat, Addis Ababa, Ethiopia.

Organization for Welfare and Development in Action, Jigjiga, Ethiopia.

出版信息

Pan Afr Med J. 2022 May 17;42:46. doi: 10.11604/pamj.2022.42.46.32856. eCollection 2022.

DOI:10.11604/pamj.2022.42.46.32856
PMID:35949467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9338724/
Abstract

INTRODUCTION

although the oral polio vaccine prevents virus transmission from person to person, it is crucial for poliovirus eradication. The continued use of live attenuated poliovirus poses an ongoing risk of circulating Vaccine Derived Poliovirus-2 (cVDPV2) outbreaks. This study assesses the response to the cVDPV2 outbreak in Dollo Zone, Somali Region, Ethiopia.

METHODS

after examining and verifying the occurrence of the outbreak, a team was established and prepared by resource mobilization, advocacy, and social mobilization. The group endorsed a four-step vaccination strategy, first the rapid response within 14-days by vaccinating a monovalent oral poliovirus-2 (mOPV2) to all under 5-year children in the Zone. The team further enhanced Supplementary Immunization Activities (SIA) for all under-five children with repeated doses of vaccines. At the same time, the team initiated community-based surveillance of Acute Flaccid Paralysis (AFP).

RESULTS

in the rapid-response immunization, an average of 91.4% of 0-11 months old and 90.2% of 12-59 months children were vaccinated. In SIA-1, the team vaccinated an average of 88% and 97%, and in SIA-2, 94.8% and 97.6% of children 0-11 months old and 12-59 months old, respectively. The active community-based surveillance of AFP revealed the existence of the disease in a sporadic form, of which two cases were found in Bokh district.

CONCLUSION

the response to curb the outbreak of cVDPV2 has shown a flow of actions to combat the outbreak. Strengthening and formation of response teams at different levels, resource mobilization, advocacy, and social mobilization are all essential components in maximizing the response to the outbreak.

摘要

简介

虽然口服脊髓灰质炎疫苗可防止人与人之间的病毒传播,但对于消灭脊髓灰质炎病毒至关重要。持续使用减毒活脊髓灰质炎病毒会持续存在循环疫苗衍生脊髓灰质炎病毒 2 型(cVDPV2)爆发的风险。本研究评估了埃塞俄比亚索马里地区多洛地区 cVDPV2 爆发的应对情况。

方法

在检查和核实疫情发生后,成立了一个小组,并通过资源调动、宣传和社会动员进行了准备。该小组支持四步接种策略,首先在 14 天内迅速对该地区所有 5 岁以下儿童接种单价口服脊髓灰质炎病毒 2 型(mOPV2)。该小组还通过多次疫苗接种,为所有五岁以下儿童加强了补充免疫活动(SIA)。同时,该小组启动了急性弛缓性麻痹(AFP)的基于社区的监测。

结果

在快速反应免疫接种中,0-11 个月龄和 12-59 个月龄儿童的平均接种率分别为 91.4%和 90.2%。在 SIA-1 中,该小组平均为 88%和 97%接种,在 SIA-2 中,0-11 个月龄和 12-59 个月龄儿童的接种率分别为 94.8%和 97.6%。基于社区的 AFP 主动监测发现了散发性疾病的存在,在博克区发现了两例病例。

结论

遏制 cVDPV2 爆发的应对措施表明,采取了一系列行动来应对疫情。加强和组建各级应对小组、资源调动、宣传和社会动员,都是最大限度应对疫情的必要组成部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f41/9338724/785b31386b29/PAMJ-42-46-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f41/9338724/b41264c138b4/PAMJ-42-46-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f41/9338724/47f919877991/PAMJ-42-46-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f41/9338724/3cdcbefd849a/PAMJ-42-46-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f41/9338724/785b31386b29/PAMJ-42-46-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f41/9338724/b41264c138b4/PAMJ-42-46-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f41/9338724/47f919877991/PAMJ-42-46-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f41/9338724/3cdcbefd849a/PAMJ-42-46-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f41/9338724/785b31386b29/PAMJ-42-46-g004.jpg

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