Laboratory of Pathological Anatomy, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Oujda, Morocco.
Pan Afr Med J. 2022 May 19;42:57. doi: 10.11604/pamj.2022.42.57.29748. eCollection 2022.
Biliary hamartoma, also known as biliary micro hamartoma or Von Meyenburg complex, is a rare benign liver lesion, thought to be a ductal plate malformation rather than a true neoplasm. It is often seen incidentally on imagery or surgery as multiple small subcapsular nodules, scattered throughout the liver, making it likely to be mistaken for metastatic nodules. The histological presentation can also be deceptive, leading to the misdiagnosis of an adenocarcinoma of hepato-biliary differentiation or a metastasis. We hereby present two cases of biliary hamartoma, found incidentally on imagery and surgery, the first one in a 94-year-old woman, and the second in a 48-year-old man, which was initially misdiagnosed as an adenocarcinoma, along with a discussion of key clinical and pathological findings to help avoid this diagnostic pitfall.
胆管错构瘤，又称胆管微小错构瘤或 Von Meyenburg 复合体，是一种罕见的良性肝脏病变，被认为是胆管板畸形而非真性肿瘤。它通常在影像学或手术中偶然发现为多个散在分布于肝脏表面的小结节，因此容易误诊为转移瘤。其组织学表现也具有欺骗性，导致误诊为肝内胆管细胞癌或转移癌。本文报道了两例胆管错构瘤，均为偶然发现，一例发生于 94 岁女性，另一例发生于 48 岁男性，最初均误诊为腺癌，并讨论了关键的临床和病理发现，以帮助避免这种诊断陷阱。
