Marinaccio Leonardo, Giacopelli Daniele, Ginocchio Giuliana, Vetta Francesco, Marchese Domenico
Department of Cardiology, Immacolata Concezione Hospital, Piove di Sacco, PD, Italy.
Clinical Unit, Biotronik Italia, Vimodrone, MI, Italy.
J Cardiol Cases. 2022 Apr 16;26(2):126-129. doi: 10.1016/j.jccase.2022.03.015. eCollection 2022 Aug.
Closed-loop stimulation (CLS; BIOTRONIK SE & Co. KG, Berlin, Germany) is a rate-responsive algorithm that analyzes intracardiac impedance trends using a standard lead placed in the right ventricle. It is unknown whether CLS could perform adequately with His bundle (HB) lead placement, as contractility dynamics may be attenuated in this region compared to the right ventricle apex.We performed hand-grip, mental, and bicycle exercise tests in a patient with brady atrial fibrillation and permanent HB pacing. The CLS algorithm responded with an appropriate heart rate to mental and physical tests.
A combination of permanent His bundle and closed-loop stimulation-driven pacing may be a valid and physiological option for atrial fibrillation patients with chronotropic incompetence.
闭环刺激(CLS;德国柏林百多力公司)是一种频率适应性算法,它使用置于右心室的标准导联分析心内阻抗趋势。目前尚不清楚在希氏束(HB)导联植入情况下CLS是否能充分发挥作用,因为与右心室心尖相比,该区域的收缩动力学可能会减弱。我们对一名患有缓慢性心房颤动且永久性HB起搏的患者进行了握力、精神及踏车运动试验。CLS算法在精神和身体测试中对心率做出了适当反应。
永久性希氏束起搏与闭环刺激驱动起搏相结合,对于变时功能不全的心房颤动患者可能是一种有效的生理性选择。