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经皮抽吸栓子切除术对患有Fontan循环的成年肺血栓栓塞症患者有益。

Percutaneous aspiration embolectomy is beneficial for pulmonary thromboembolism in adult patients with Fontan circulation.

作者信息

Kodama Hiroyuki, Shiina Yumi, Kijima Yasufumi, Nishihata Yosuke, Niwa Koichiro

机构信息

Department of Cardiology, St. Luke's International Hospital, Tokyo, Japan.

出版信息

J Cardiol Cases. 2022 Mar 31;26(2):101-103. doi: 10.1016/j.jccase.2022.03.006. eCollection 2022 Aug.

Abstract

UNLABELLED

In patients with acute pulmonary thromboembolism (PTE), increased pulmonary vascular resistance (PVR) due to thrombus sometimes causes hemodynamic instability, requiring reperfusion therapy with drugs, surgery, or catheterization. In particular, patients with Fontan circulation, which is strongly affected by PVR, are prone to hemodynamic instability. Moreover, these patients sometimes have bleeding complications such as hemoptysis and intrathoracic adhesions, following multiple prior thoracotomies, making it difficult to choose pharmacotherapy. Percutaneous aspiration embolectomy (PAE) is a useful treatment option because it minimizes bleeding complications, is less invasive, and more rapid than surgery, and is easy to perform. Herein, we report two cases of Fontan patients having PTE treated with PAE. In Case 1, a 21-year-old man with a history of a Fontan procedure suddenly developed acute PTE, for which anticoagulants were administered immediately. However, his condition was refractory to treatment and he underwent PAE on the third day of illness. In Case 2, a 28-year-old woman with a history of Fontan procedure who had been on anticoagulants, developed acute PTE on the ninth postpartum day, and underwent PAE on the day of onset. In both cases, the respiratory condition improved, and re-treatment for PTE was not required.

LEARNING OBJECTIVE

Fontan patients with acute pulmonary thromboembolism often require reperfusion therapy because they can easily become hemodynamically unstable due to increased pulmonary vascular resistance. For them, who often have adhesions following multiple prior thoracotomies and bleeding complications, percutaneous aspiration embolectomy may be effective as it has minimal bleeding risk and is minimally invasive, rapid, and straightforward.

摘要

未标注

在急性肺血栓栓塞症(PTE)患者中,血栓导致的肺血管阻力(PVR)增加有时会引起血流动力学不稳定,需要通过药物、手术或导管介入进行再灌注治疗。特别是,受PVR强烈影响的Fontan循环患者容易出现血流动力学不稳定。此外,这些患者由于先前多次开胸手术,有时会出现咯血和胸腔内粘连等出血并发症,使得药物治疗的选择变得困难。经皮抽吸血栓切除术(PAE)是一种有用的治疗选择,因为它能将出血并发症降至最低,侵入性比手术小,速度更快,且操作简便。在此,我们报告两例接受PAE治疗的Fontan患者PTE病例。病例1,一名21岁有Fontan手术史的男性突然发生急性PTE,立即给予抗凝治疗。然而,他的病情对治疗无效,在发病第三天接受了PAE。病例2,一名28岁有Fontan手术史且一直在接受抗凝治疗的女性,在产后第九天发生急性PTE,并在发病当天接受了PAE。两例患者的呼吸状况均有所改善,无需再次进行PTE治疗。

学习目标

Fontan循环的急性肺血栓栓塞症患者常需要再灌注治疗,因为肺血管阻力增加容易导致血流动力学不稳定。对于这些因先前多次开胸手术常伴有粘连和出血并发症的患者,经皮抽吸血栓切除术可能有效,因为其出血风险最小,侵入性最小,速度快且操作简单。

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Transcatheter pulmonary embolectomy after fontan.Fontan术后经导管肺动脉血栓切除术
Catheter Cardiovasc Interv. 2016 Apr;87(5):939-44. doi: 10.1002/ccd.26096. Epub 2015 Jul 8.

本文引用的文献

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Transcatheter pulmonary embolectomy after fontan.Fontan术后经导管肺动脉血栓切除术
Catheter Cardiovasc Interv. 2016 Apr;87(5):939-44. doi: 10.1002/ccd.26096. Epub 2015 Jul 8.
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The Fontan circulation: who controls cardiac output?Fontan循环:谁控制心输出量?
Interact Cardiovasc Thorac Surg. 2010 Mar;10(3):428-33. doi: 10.1510/icvts.2009.218594. Epub 2009 Dec 7.

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