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急性肺栓塞的外科取栓术:系统评价与综合荟萃分析

Surgical Embolectomy for Acute Pulmonary Embolism: Systematic Review and Comprehensive Meta-Analyses.

作者信息

Kalra Rajat, Bajaj Navkaranbir S, Arora Pankaj, Arora Garima, Crosland William A, McGiffin David C, Ahmed Mustafa I

机构信息

Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, and Cardiovascular Division, University of Minnesota, Minneapolis, Minnesota.

Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama; Division of Cardiovascular Medicine and Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

出版信息

Ann Thorac Surg. 2017 Mar;103(3):982-990. doi: 10.1016/j.athoracsur.2016.11.016. Epub 2017 Jan 31.

Abstract

Surgical pulmonary embolectomy (SPE) is a viable treatment approach for subsets of patients with acute pulmonary embolism. However, outcomes data are limited. We sought to characterize mortality and safety outcomes for this population. Studies reporting inhospital mortality for patients undergoing SPE for acute pulmonary embolism were included. In 56 eligible studies, we found 1,579 patients who underwent 1,590 SPE operations. The pooled inhospital all-cause mortality rate was 26.3% (95% confidence interval: 22.5% to 30.5%). Surgical site complications occurred in 7.0% of operations (95% confidence interval: 4.9% to 9.8%). More investigation is required to define the patient population that would benefit the most from SPE.

摘要

外科肺动脉血栓切除术(SPE)是治疗急性肺栓塞部分患者的一种可行方法。然而,相关结果数据有限。我们试图描述该人群的死亡率和安全性结果。纳入了报告急性肺栓塞患者接受SPE治疗的住院死亡率的研究。在56项符合条件的研究中,我们发现1579例患者接受了1590次SPE手术。汇总的住院全因死亡率为26.3%(95%置信区间:22.5%至30.5%)。7.0%的手术发生了手术部位并发症(95%置信区间:4.9%至9.8%)。需要更多研究来确定最能从SPE中获益的患者群体。

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