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一名患有新冠病毒病的年轻免疫功能低下糖尿病患者发生毛霉菌病继发脓胸合并支气管胸膜瘘的罕见病例

A Rare Case of Empyema Complicated With Bronchopleural Fistula Secondary to Mucormycosis in a Young Immunocompromised Diabetic Patient With COVID-19.

作者信息

Risal Ruby, Jahir Tahmina, Islam Ratul, Noel Pharlin, Subedi Kamal R, Khan Ahmad, Kumari Aneeta, Schmidt Marie

机构信息

Pulmonary Medicine, Interfaith Medical Center, Brooklyn, USA.

Medicine, American University of Antigua, New York, USA.

出版信息

Cureus. 2022 Jul 7;14(7):e26635. doi: 10.7759/cureus.26635. eCollection 2022 Jul.

DOI:10.7759/cureus.26635
PMID:35949757
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9356580/
Abstract

Mucormycosis is an opportunistic fungal infection caused by the zygomycetes Mucor and Rhizopus. Most documented conditions and risk factors that predispose to mucormycosis are uncontrolled diabetes mellitus (DM), with or without ketoacidosis, hematological malignancies (HM), transplantation, immunosuppression, and chronic sinusitis. Pulmonary empyema secondary to Mucor in coronavirus disease 2019 (COVID-19)-infected patients is rarely documented. Here we present an extremely rare case of pulmonary empyema secondary to Mucor infection complicated by bronchocutaneous fistula in a human immunodeficiency virus (HIV)-infected patient in the setting of acute COVID-19 infection.

摘要

毛霉病是一种由毛霉目真菌毛霉属和根霉属引起的机会性真菌感染。大多数已记录的易患毛霉病的情况和危险因素包括未控制的糖尿病（DM），伴或不伴有酮症酸中毒、血液系统恶性肿瘤（HM）、移植、免疫抑制和慢性鼻窦炎。2019冠状病毒病（COVID-19）感染患者继发于毛霉的肺脓肿鲜有记录。在此，我们报告一例极其罕见的病例，该病例为一名人类免疫缺陷病毒（HIV）感染患者在急性COVID-19感染背景下继发于毛霉感染的肺脓肿，并伴有支气管皮肤瘘。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/edc39f8d067f/cureus-0014-00000026635-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/914272a1c437/cureus-0014-00000026635-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/68d90be773ed/cureus-0014-00000026635-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/9608d0aa99e9/cureus-0014-00000026635-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/67f261b96a38/cureus-0014-00000026635-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/1c1c76bb3020/cureus-0014-00000026635-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/edc39f8d067f/cureus-0014-00000026635-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/914272a1c437/cureus-0014-00000026635-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/68d90be773ed/cureus-0014-00000026635-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/9608d0aa99e9/cureus-0014-00000026635-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/67f261b96a38/cureus-0014-00000026635-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/1c1c76bb3020/cureus-0014-00000026635-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a76c/9356580/edc39f8d067f/cureus-0014-00000026635-i06.jpg

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本文引用的文献

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