Jawad Ali, Hannouneh Zein Alabdin, Salame Hadi, Taher Hussein, Alkharat Banan
Faculty of Medicine, Damascus university, Damascus, Syrian Arab Republic.
Faculty of Medicine, Al Andalus University for Medical Sciences, Tartus, Syrian Arab Republic.
Heliyon. 2024 Jun 15;10(12):e32906. doi: 10.1016/j.heliyon.2024.e32906. eCollection 2024 Jun 30.
Mucormycosis is an opportunistic fungal infection that primarily affects immunocompromised individuals and rarely presents as renal mucormycosis (RM). Diagnosis can be challenging for many physicians. We report a rare case of primary, unilateral RM which triggered diabetic ketoacidosis in a type 2 diabetic patient. The case was later complicated by a bronchopleural fistula and a meropenem-resistant infection. The patient was ultimately treated with surgical intervention, liposomal amphotericin B, and polymyxine E. Early diagnosis and timely treatment of this life-threatening disease and its complications are significant in reducing mortality.
毛霉菌病是一种机会性真菌感染,主要影响免疫功能低下的个体,很少表现为肾毛霉菌病(RM)。对许多医生来说,诊断可能具有挑战性。我们报告了一例罕见的原发性单侧RM病例,该病例在一名2型糖尿病患者中引发了糖尿病酮症酸中毒。该病例后来并发支气管胸膜瘘和耐美罗培南感染。患者最终接受了手术干预、脂质体两性霉素B和多粘菌素E治疗。对这种危及生命的疾病及其并发症进行早期诊断和及时治疗对于降低死亡率至关重要。