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立体定向放射外科作为控制泪腺脑膜转移性腺样囊性癌的成功方法:一例报告

Stereotactic radiosurgery as a successful method to control meningeal metastatic adenoid cystic carcinoma of the lacrimal gland: A case report.

作者信息

Salim Nidal, Libson Evgeniy, Tumanova Kristina, Krotenkova Irina

机构信息

Department of Radiation Oncology, European Medical Center, Moscow 129090, Russia.

Department of Diagnostic Imaging, European Medical Center, Moscow 129090, Russia.

出版信息

Mol Clin Oncol. 2022 Jul 14;17(3):135. doi: 10.3892/mco.2022.2568. eCollection 2022 Sep.

Abstract

Adenoid cystic carcinoma (ACC) of the lacrimal gland is a rare tumor. In addition, considering the lack of data on large groups of patients there is no standard of care to treat patients with multiple meningeal metastases of ACC. A two-year analysis of the course of the disease in a patient with synchronous oligometastatic ACC of the lacrimal gland that was treated with stereotactic radiosurgery (SRS) is presented. The aim of the present case report was to evaluate the effect of SRS in the treatment of a patient with ACC. Preliminary results confirmed that this method was highly effective in this patient. The patient is currently living with a good quality of life, normal vision and with no evidence of disease or complications. SRS exhibited reliable local tumor control and insignificant radiation-related complications, rendering it an encouraging treatment option for patients with recurrent or metastatic ACC.

摘要

泪腺腺样囊性癌(ACC)是一种罕见肿瘤。此外,鉴于缺乏关于大量患者的数据,目前尚无治疗伴有多发脑膜转移的ACC患者的标准治疗方案。本文报告了1例接受立体定向放射外科治疗(SRS)的同步寡转移泪腺ACC患者的两年病程分析。本病例报告的目的是评估SRS对ACC患者的治疗效果。初步结果证实,该方法对该患者疗效显著。该患者目前生活质量良好,视力正常,无疾病或并发症迹象。SRS显示出可靠的局部肿瘤控制效果,且辐射相关并发症不明显,使其成为复发或转移性ACC患者令人鼓舞的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ae6/9353865/87fadaaf7310/mco-17-03-02568-g00.jpg

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