Toyonaga Haruka, Kin Toshifumi, Iwano Kosuke, Nakamura Risa, Shimizu Takao, Chikugo Koki, Ishii Tatsuya, Nasuno Hiroshi, Hayashi Tsuyoshi, Takahashi Kuniyuki, Yamazaki Hajime, Katanuma Akio
Center for Gastroenterology Teine Keijinkai Hospital Hokkaido Japan.
Department of Community Medicine, Section of Clinical Epidemiology, Graduate School of Medicine Kyoto University Kyoto Japan.
DEN Open. 2022 Aug 4;3(1):e158. doi: 10.1002/deo2.158. eCollection 2023 Apr.
Endoscopic ultrasonography is an important examination for periampullary diseases. The duodenum is filled with water to ensure a clear image and distend the duodenal wall without burying the papilla within duodenal folds; however, peristalsis frequently makes it difficult to maintain water within the duodenum. The gel immersion method (intestine is filled with viscosity gel) has recently been attracting attention. We evaluated the usefulness of using this method for endoscopic ultrasonography to detect and delineate the major duodenal papilla.
Fifty-nine consecutive patients who underwent gel immersion-endoscopic ultrasonography between February and March 2021 were included retrospectively. The papilla was observed by filling the duodenum with clear viscosity gel. Outcomes were the rate of duodenal distention, delineation rates of the papilla, the time required for delineation, volume of the gel used, and adverse events.
Duodenal distention was excellent, good, and poor in 58%, 34%, and 7% of cases, respectively. The delineation rates of the papilla in the axial and longitudinal views were 98% and 66%, respectively. The median time required to delineate the papilla in each view was 3.1 (range, 1.0-1.4) and 7.9 (1.9-28.6) min; the median volume of the gel used was 80 (30-150) ml and 100 (50-200) ml, respectively. No adverse events were noted.
Gel immersion-endoscopic ultrasonography provided sufficient duodenal distention, leading to high rates of detection and delineation of the papilla using a small volume of gel within a short time. This method may be useful for the evaluation of the ampullary region.
内镜超声检查是壶腹周围疾病的重要检查方法。十二指肠需充满水以确保图像清晰,并使十二指肠壁扩张而不将乳头埋入十二指肠皱襞内;然而,蠕动常常使十二指肠内难以保持水的存在。凝胶浸泡法(肠内充满粘性凝胶)最近受到了关注。我们评估了使用这种方法进行内镜超声检查以检测和描绘十二指肠大乳头的实用性。
回顾性纳入了2021年2月至3月间连续接受凝胶浸泡内镜超声检查的59例患者。通过向十二指肠内注入透明粘性凝胶来观察乳头。观察指标包括十二指肠扩张率、乳头描绘率、描绘所需时间、所用凝胶体积以及不良事件。
十二指肠扩张情况优、良、差的病例分别占58%、34%和7%。乳头在轴位和纵位视图中的描绘率分别为98%和66%。在每个视图中描绘乳头所需的中位时间分别为3.1(范围1.0 - 1.4)分钟和7.9(1.9 - 28.6)分钟;所用凝胶的中位体积分别为80(30 - 150)毫升和100(50 - 200)毫升。未观察到不良事件。
凝胶浸泡内镜超声检查可使十二指肠充分扩张,在短时间内使用少量凝胶即可实现较高的乳头检测和描绘率。该方法可能有助于壶腹区域的评估。