Department of Surgery, International Medical University, Clinical campus, Seremban, 70300, Negeri Sembilan, Malaysia.
Department of Surgery, CMH Specialist Hospital, Seremban, 70200, Negeri Sembilan, Malaysia.
Ghana Med J. 2021 Sep;55(3):226-228. doi: 10.4314/gmj.v55i3.8.
Cholelithiasis can present from a milder form of biliary colic to a more severe and complicated one like empyema gallbladder and a lesser-known variant of gangrenous gallbladder called marbleization of the gallbladder. The clinical signs and symptoms are similar to acute cholecystitis. Diabetes mellitus could have a role in the process of marbleization. Diagnosing marbleization of the gall bladder is not easy preoperatively. Computerized tomography is a better diagnostic modality when compared to laboratory investigations. Urgent cholecystectomy is the only option, and there is no role of conservative treatment. We report a case of a 36-year-old man with newly diagnosed Diabetes Mellitus diagnosed initially as acute cholecystitis and managed conservatively. He did not respond to treatment and hence underwent cholecystectomy and intraoperatively was found to have marbleization of the gall bladder.
胆石病可表现为较轻的胆绞痛,也可表现为更严重和复杂的疾病,如胆囊积脓和一种鲜为人知的坏疽性胆囊病变,称为胆囊大理石样变。其临床体征和症状与急性胆囊炎相似。糖尿病可能在大理石样变的过程中起作用。术前诊断胆囊大理石样变并不容易。与实验室检查相比,计算机断层扫描是一种更好的诊断方式。紧急胆囊切除术是唯一的选择,保守治疗没有作用。我们报告了一例 36 岁男性,患有新诊断的糖尿病,最初被诊断为急性胆囊炎并接受保守治疗。他对治疗没有反应,因此进行了胆囊切除术,术中发现胆囊大理石样变。