du Cret R P, Choi R E, Roe S J, Boudreau R J, Park H M, Loken M K
Clin Nucl Med. 1987 Jun;12(6):436-9. doi: 10.1097/00003072-198706000-00006.
Estimation of thyroid mass both from parameters derived from thyroid scintigraphy and clinical palpation for purposes of therapeutic dosimetry has not been tested for accuracy. To more precisely determine thyroid mass 90 thyroid lobes from 45 autopsies without history of thyroid disease were studied. Specimens were dissected free of nonthyroidal tissue and assessed for volume, maximum depth (D), width (W), length (L) and mass (M). Using a linear regression model and applying known lobar depth, the most accurate formula to predict true lobar mass (in grams) was 4.9D + 0.07L2W-2.3 (in cms). Length and width would be obtainable in vivo from routine scintigraphic measurements (in cm) and depth would be most accurately determined by ultrasound. For most clinical circumstances where lobar depth is unknown we found the best formula for mass (g) to be 0.1L2W (in cm).
出于治疗剂量测定的目的，通过甲状腺闪烁扫描得出的参数以及临床触诊来估计甲状腺质量，其准确性尚未得到验证。为了更精确地确定甲状腺质量，我们研究了45例无甲状腺疾病病史的尸检中的90个甲状腺叶。将标本从非甲状腺组织中分离出来，并评估其体积、最大深度（D）、宽度（W）、长度（L）和质量（M）。使用线性回归模型并应用已知的叶深度，预测真实叶质量（以克为单位）的最准确公式为4.9D + 0.07L2W - 2.3（以厘米为单位）。长度和宽度可通过常规闪烁扫描测量在体内获得（以厘米为单位），而深度最准确地由超声确定。对于大多数叶深度未知的临床情况，我们发现质量（克）的最佳公式为0.1L2W（以厘米为单位）。
