Chen J H, Lin C Y, Chen W P, Tang R B, Hwang B
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1987 Feb;20(1):23-8.
A retrospective study was made of 137 children with systemic lupus erythematosus (SLE) seen at the Veterans General Hospital in the past 12 years. There were 116 females (84.7%), and 21 males (15.3%). The peak ages of onset were 13-14 years and 16-17 years. Malar rash, arthritis and fever were the most common presentations, as in previous studies. Central nervous system (CNS) involvement occurred in 24 cases (17.5%), and renal disorder was noted in 77 cases (56.2%). Renal biopsy in 67 cases showed a pathological transformation rate of 16.1% (5/31). Ten patients died during the study period, with renal insufficiency the primary cause of death.
对过去12年在荣民总医院就诊的137例系统性红斑狼疮（SLE）患儿进行了回顾性研究。其中女性116例（84.7%），男性21例（15.3%）。发病高峰年龄为13 - 14岁和16 - 17岁。如先前研究一样，颧部皮疹、关节炎和发热是最常见的表现。24例（17.5%）出现中枢神经系统（CNS）受累，77例（56.2%）有肾脏疾病。67例患者的肾活检显示病理转化率为16.1%（5/31）。研究期间有10例患者死亡，主要死亡原因是肾功能不全。
