Hennon Mark
Department of Thoracic Surgery, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14263, USA; Department of Surgery, Jacobs School of Medicine, State University of New York at Buffalo, 100 High Street, Buffalo, NY 14203, USA.
Surg Clin North Am. 2022 Aug;102(4):615-624. doi: 10.1016/j.suc.2022.05.001.
Tumors of soft tissue origin are not common but are increasing in incidence. Given the rare and heterogeneous nature of the disease, deciding on an effective treatment approach to the patient can be challenging. Approximately 20-50% of patients with sarcoma will develop metastases to the lung via hematogenous spread. Despite improvements in systemic therapy options for patients with metastatic disease to the lung, surgical resection of metastases is often the preferred option in patients who are safe surgical candidates. Clearance of metastatic disease with surgical resection has been proven to be cost-effective and can improve chances for long term survival. Deciding on who may benefit from surgical resection is best achieved in a multidisciplinary setting.
软组织来源的肿瘤并不常见，但发病率正在上升。鉴于该疾病罕见且具有异质性，为患者确定有效的治疗方法可能具有挑战性。大约20%-50%的肉瘤患者会通过血行转移至肺部。尽管针对肺转移患者的全身治疗选择有所改善，但对于适合手术的患者，手术切除转移灶通常是首选方案。手术切除转移病灶已被证明具有成本效益，并且可以提高长期生存的机会。确定谁可能从手术切除中获益，最好在多学科环境中进行。
