Department of Allied Health Sciences, University of Connecticut, Storrs, CT 06269, USA.
Institute for Collaboration on Health, Intervention, and Policy (InCHIP), University of Connecticut, Storrs, CT 06269, USA.
Int J Environ Res Public Health. 2022 Aug 1;19(15):9430. doi: 10.3390/ijerph19159430.
Cognitive dysfunction is prevalent among persons on medication for opioid use disorder (MOUD). This cognitive dysfunction has been shown to reduce HIV treatment engagement and medication adherence. We investigated the impact of integrating specific behavioral strategies into an HIV prevention session to accommodate cognitive dysfunction among people on MOUD. Patients on MOUD (n = 20) were randomized to one of two different HIV prevention conditions. The same HIV risk reduction content was presented to both conditions; however, the experimental condition had accommodation strategies integrated into the session. Participants completed a skills checklist at pre-, post-, and 2-week follow-up to examine the level of HIV risk reduction content learned and utilized over time. Participants in the experimental condition indicated high acceptability (95%) for the accommodation strategies. These participants also demonstrated greater improvement in the ability to properly clean a syringe, from pre- to post- (p < 0.02) and from pre- to follow-up (p < 0.02) when compared to participants in the standard condition. Results from this pilot study indicate that accommodation strategies improved participants’ ability to learn, retain, and utilize risk reduction skills over time. This foundation of research indicates a promising, innovative strategy to increase the ability for persons on MOUD to engage in HIV prevention behaviors.
认知功能障碍在接受阿片类药物使用障碍（MOUD）药物治疗的人群中很常见。这种认知功能障碍已被证明会降低 HIV 治疗的参与度和药物依从性。我们研究了在 HIV 预防课程中整合特定行为策略，以适应接受 MOUD 药物治疗的人群的认知功能障碍的影响。接受 MOUD 药物治疗的患者（n = 20）被随机分配到两种不同的 HIV 预防条件之一。两种条件都呈现了相同的 HIV 风险降低内容；然而，实验组的课程中整合了适应策略。参与者在预、后和 2 周随访时完成了技能检查表，以检查随时间推移学习和使用的 HIV 风险降低内容的水平。实验组的参与者对适应策略的接受度很高（95%）。与标准条件组相比，这些参与者在适当清洁注射器的能力方面也表现出了更大的改善，从预到后（p < 0.02），从预到随访（p < 0.02）。这项试点研究的结果表明，适应策略提高了参与者随时间学习、保留和运用风险降低技能的能力。这项研究的基础表明，这是一种有前途的、创新的策略，可以提高接受 MOUD 药物治疗的人群参与 HIV 预防行为的能力。
