酒精乙氧基化物在鲤鱼（Cyprinus carpio）中的生物富集。
Bioconcentration of alcohol ethoxylates in carp (Cyprinus carpio).
作者信息
Wakabayashi M, Kikuchi M, Sato A, Yoshida T
出版信息
Ecotoxicol Environ Saf. 1987 Apr;13(2):148-63. doi: 10.1016/0147-6513(87)90002-9.
The uptake, distribution, and clearance of three labeled nonionic surfactants, 14C-labeled dodecyl tetra(oxyethylene) ether [14C-C12-AE(4)], 14C-labeled dodecyl octa(oxyethylene) ether [14C-C12-AE(8)], and 14C-labeled dodecyl hexadeca(oxyethylene) ether [14C-C12-AE(16)] were investigated in carp (Cyprinus carpio) exposed to concentrations of 0.2-0.6 mg X liter-1, using whole-body autoradiography and the liquid scintillation counting method. 14C radioactivity was rapidly absorbed into the fish body and distributed in skin, nasal and oral cavities, gills, brain, hepatopancreas, kidney, gall bladder, and intestinal content at comparatively high concentrations. The calculated wet weight whole-body bioconcentration factor at steady state in the fish exposed to 14C-C12-AE(4), 14C-C12-AE(8), or 14C-C12-AE(16) for 72 hr was 310, 220, or 4.3, respectively. Clearance of 14C radioactivity from the fish body was rapid, with half-lives of 30-80 hr. The metabolites of 14C-C12-AE(4) were also examined in gills, blood, kidney, hepatopancreas, or gall bladder by thin-layer chromatography.
采用全身放射自显影和液体闪烁计数法，研究了鲤鱼（Cyprinus carpio）暴露于浓度为0.2 - 0.6毫克/升的三种标记非离子表面活性剂，即14C标记的十二烷基四（氧乙烯）醚[14C-C12-AE(4)]、14C标记的十二烷基八（氧乙烯）醚[14C-C12-AE(8)]和14C标记的十二烷基十六（氧乙烯）醚[14C-C12-AE(16)]后的摄取、分布和清除情况。14C放射性迅速被吸收进鱼体，并以相对较高的浓度分布在皮肤、鼻腔和口腔、鳃、脑、肝胰腺、肾脏、胆囊和肠道内容物中。在暴露于14C-C12-AE(4)、14C-C12-AE(8)或14C-C12-AE(16) 72小时的鱼中，计算得出的稳态湿重全身生物浓缩系数分别为310、220或4.3。14C放射性从鱼体的清除速度很快，半衰期为30 - 80小时。还通过薄层色谱法在鳃、血液、肾脏、肝胰腺或胆囊中检测了14C-C12-AE(4)的代谢产物。
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