Institute for Ophthalmic Research, 72076 Tübingen, Germany.
Carl Zeiss Vision International GmbH, 73430 Aalen, Germany.
Int J Environ Res Public Health. 2022 Aug 4;19(15):9571. doi: 10.3390/ijerph19159571.
The present study investigates the effects of peripheral spatial cues and optically distorting augmentations over eccentric vision mechanisms in normally sighted participants with simulated scotoma. Five different augmentations were tested inside a virtual reality (VR)-gaming environment. Three were monocular spatial cues, and two were binocular optical distortions. Each was divided into three conditions: baseline with normal viewing, augmentation with one of the assistance methods positioned around the scotoma, and one with only the simulated central scotoma. The study found that the gaming scenario induced eccentric viewing for the cued augmentation groups, even when the peripheral assistance was removed, while for the optical distortions group, the eccentric behavior disappeared after the augmentation removal. Additionally, an upwards directionality of gaze relative to target during regular gaming was found. The bias was maintained and implemented during and after the cued augmentations but not after the distorted ones. The results suggest that monocular peripheral cues could be better candidates for implementing eccentric viewing training in patients. At the same time, it showed that optical distortions might disrupt such behavior. Such results are noteworthy since distortions such as zoom are known to help patients with macular degeneration see targets of interest.
本研究旨在调查外周空间提示和光变形对正常视力参与者模拟视野缺损的偏心视觉机制的影响。在虚拟现实（VR）游戏环境中测试了五种不同的增强方法。其中三种是单眼空间提示，两种是双眼光学变形。每个方法都分为三种情况：正常视图的基线、增强辅助方法放置在视野缺损周围的增强以及仅模拟中央视野缺损的增强。研究发现，即使在去除外周辅助的情况下，游戏场景也会引起提示增强组的偏心观看，而对于光学变形组，在去除增强后，偏心行为消失。此外，在正常游戏期间，相对于目标的注视方向向上。在提示增强期间和之后，这种偏差得以维持和实施，但在变形之后则没有。结果表明，单眼外周提示可能是在患者中实施偏心观看训练的更好候选方法。同时，结果表明光学变形可能会破坏这种行为。由于已知诸如变焦等变形可以帮助黄斑变性患者看到感兴趣的目标，因此这些结果值得注意。
