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膳食纤维(燕麦麸)补充对高血压患者心率降低的影响:一项随机 DASH 饮食对照临床试验。

Effect of Dietary Fiber (Oat Bran) Supplement in Heart Rate Lowering in Patients with Hypertension: A Randomized DASH-Diet-Controlled Clinical Trial.

机构信息

Nursing Department, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Nursing Department, The Yancheng School of Clinical Medicine, Nanjing Medical University, Yancheng 224000, China.

出版信息

Nutrients. 2022 Jul 30;14(15):3148. doi: 10.3390/nu14153148.

Abstract

(1) Background: The management goal for patients with essential hypertension (HTN) is not only to lower blood pressure (BP), but also to control increased heart rate (HR). In a previous study, it was found that dietary fiber (DF) supplementation can effectively reduce BP in patients with HTN. The aim of this study was to determine whether a DF supplement can lower HR in patients with HTN. (2) Methods: Seventy patients who met the inclusion and exclusion criteria were randomly allocated into the control group ( = 34) and the intervention group ( = 36). The regular DASH dietary care was delivered to both groups of patients. In addition, one bag of oat bran (30 g/d, containing DF 8.9 g) was delivered to the intervention group. The 24 h ambulatory heart rate was measured at baseline and 3 months. (3) Results: At 3 months, the 24 h maximum heart rate (24h maxHR) in the intervention group was significantly lower than that in the control group. After the intervention, within-group comparisons in the intervention group revealed that there were significant reductions in the 24 h average heart rate (24h aveHR), 24h maxHR, average heart rate during day time (D-aveHR), minimum heart rate during day time (D-minHR), and maximum heart rate during day time (D-maxHR). Similar differences were not found in the control group. (4) Conclusions: Dietary fiber (oat bran) supplementation might be beneficial in lowering HR in patients with HTN.

摘要

(1)背景:原发性高血压(HTN)患者的治疗目标不仅在于降低血压(BP),还在于控制心率(HR)的升高。在之前的研究中发现,膳食纤维(DF)补充剂可以有效降低 HTN 患者的血压。本研究旨在确定 DF 补充剂是否可以降低 HTN 患者的 HR。(2)方法:将符合纳入和排除标准的 70 名患者随机分配到对照组(n=34)和干预组(n=36)。两组患者均给予常规 DASH 饮食护理。此外,干预组每天给予 1 袋燕麦麸(30 g/d,含 DF 8.9 g)。分别在基线和 3 个月时测量 24 h 动态心率。(3)结果:3 个月时,干预组的 24 h 最大心率(24h maxHR)明显低于对照组。干预后,干预组组内比较显示,24 h 平均心率(24h aveHR)、24h maxHR、白天平均心率(D-aveHR)、白天最小心率(D-minHR)和白天最大心率(D-maxHR)均显著降低。对照组则未发现类似差异。(4)结论:膳食纤维(燕麦麸)补充可能有益于降低 HTN 患者的 HR。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97be/9370281/4d6d5138006a/nutrients-14-03148-g001.jpg

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