拟南芥中该基因家族的表达与功能分析。

Expression and Functional Analyses of the Gene Family in Arabidopsis.

作者信息

Diaz-Ramirez David, Diaz-Garcia Ury Sarai, Magdaleno-Garcia Guadalupe, Huep Gunnar, Appelhagen Ingo, Sagasser Martin, Marsch-Martinez Nayelli

机构信息

Department of Biotechnology and Biochemistry, Center for Research and Advanced Studies of the National Polytechnic Institute, Irapuato 36824, Mexico.

Genetics and Genomics of Plants, Faculty of Biology, Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany.

出版信息

Plants (Basel). 2022 Aug 1;11(15):2010. doi: 10.3390/plants11152010.

DOI:10.3390/plants11152010

PMID:35956487

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9425439/

Abstract

The WIP family of transcription factors comprises the A1d subgroup of C2H2 zinc finger proteins. This family has six members in and most of the known functions have been described by analyzing single knockout mutants. However, it has been shown that and its closest paralogs and have a redundant and essential function in root meristems. It is likely that these and other genes perform more, still unknown, functions. To obtain hints about these other functions, the expression of the six genes was explored. Moreover, phenotypic ana-lyses of overexpressors and mutants revealed functions in modulating organ and cell size, stomatal density, and vasculature development.

摘要

WIP转录因子家族由C2H2锌指蛋白的A1d亚组组成。该家族在拟南芥中有六个成员，并且大多数已知功能是通过分析单基因敲除突变体来描述的。然而，已经表明，WIP1及其最接近的旁系同源基因WIP2和WIP3在根分生组织中具有冗余且必不可少的功能。这些基因以及其他WIP基因可能还具有更多未知功能。为了获得有关这些其他功能的线索，研究了六个WIP基因的表达。此外，对过表达植株和WIP突变体的表型分析揭示了它们在调节器官和细胞大小、气孔密度以及维管系统发育方面的功能。