Parasitology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt.
Department of Veterinary Medicine, University of Sassari, Sassari, Italy.
Parasitology. 2022 Oct;149(12):1607-1622. doi: 10.1017/S0031182022001123. Epub 2022 Aug 12.
In the present study, all published data on the epidemiology and molecular characters of were systematically collected from relevant databases (e.g. PubMed, Scopus, National Center for Biotechnology Information), and combined in various statistical and genetic analyses as a contribution to a better understanding of the epidemiology of this ubiquitous taeniid worldwide. While 5.8% of the key hosts (dogs) from various countries had , grey wolves displayed the highest prevalence (21.6%) among the definitive hosts. Small ruminants are the main intermediate hosts and carry the coenuri in various locations, but most commonly in the central nervous system (CNS). Cerebral coenuri were confirmed in 53% of sheep exhibiting neurological symptoms, and infected animals often had only a single coenurus in the brain. Sheep had a higher prevalence (8.8%) of CNS coenuri than goats (5.8%); however, extra-CNS coenuri were detected more frequently in goats than in sheep. In either case, the difference between sheep and goats was statistically insignificant. Analysis of 233 partial cytochrome oxidase subunit I nucleotide sections for revealed high haplotype and low nucleotide diversities. Fifty-one haplotypes were detected circulating in 6 geographic populations. China, Iran and Turkey had 2 major haplotypes, whereas Italy and Egypt shared 3. Haplotypes from Greece circulate worldwide, and displayed similar gene flow values when compared with the other populations. There were no distinct patterns for haplotype distribution in relation to the infected hosts or coenuri locations. The existence of genetic variants in was highlighted, but needs further studies.
在本研究中，从相关数据库（例如 PubMed、Scopus、美国国家生物技术信息中心）系统地收集了有关的流行病学和分子特征的所有已发表数据，并结合各种统计和遗传分析，以增进对这种无处不在的带绦虫全世界流行病学的理解。虽然来自不同国家的主要宿主（狗）的 5.8%携带了该寄生虫，但终末宿主中的灰狼显示出最高的流行率（21.6%）。小反刍动物是主要的中间宿主，在不同部位携带囊尾蚴，但最常见于中枢神经系统（CNS）。脑囊尾蚴在 53%表现出神经症状的绵羊中得到证实，感染动物的大脑中通常只有单个囊尾蚴。绵羊的中枢神经系统囊尾蚴患病率（8.8%）高于山羊（5.8%）；然而，在山羊中比在绵羊中更频繁地检测到额外的中枢神经系统囊尾蚴。在任何一种情况下，绵羊和山羊之间的差异均无统计学意义。对 233 个部分细胞色素氧化酶亚单位 I 核苷酸片段的分析表明，存在高度的单倍型和低核苷酸多样性。在 6 个地理种群中检测到 51 种单倍型。中国、伊朗和土耳其有 2 种主要的单倍型，而意大利和埃及则有 3 种。来自希腊的单倍型在全球范围内传播，并与其他种群相比显示出相似的基因流动值。在与感染宿主或囊尾蚴位置相关的单倍型分布方面没有明显的模式。强调了 中存在遗传变异，但需要进一步研究。
