• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

新冠病毒感染后巨细胞性心肌炎经免疫抑制治疗成功治愈

Giant cell myocarditis following COVID-19 successfully treated by immunosuppressive therapy.

作者信息

Amiri Afsaneh, Houshmand Golnaz, Taghavi Sepideh, Kamali Monireh, Faraji Mona, Naderi Nasim

机构信息

Rajaie Cardiovascular Medical and Research Center School of medicine, Iran University of Medical Sciences Tehran Iran.

出版信息

Clin Case Rep. 2022 Aug 9;10(8):e6196. doi: 10.1002/ccr3.6196. eCollection 2022 Aug.

DOI:10.1002/ccr3.6196
PMID:35957785
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9361461/
Abstract

It has been shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), by coronavirus disease 2019 (COVID-19), can lead to multi-organ impairment including cardiac involvement and immunological problems. Acute myocarditis is one of serious and fatal complications of COVID-19. In this case report, we present a 46-year-old lady with a history of lichen planus dermatitis who has developed a rapidly progressive heart failure after an episode of COVID-19. The pathologic examination of her endomyocardial biopsy specimens was compatible with GCM, and she was successfully treated with a combined immunosuppressive therapy regimen.

摘要

已有研究表明，2019冠状病毒病（COVID-19）的致病源严重急性呼吸综合征冠状病毒2（SARS-CoV-2）可导致多器官损害，包括心脏受累和免疫问题。急性心肌炎是COVID-19严重且致命的并发症之一。在本病例报告中，我们介绍了一位有扁平苔藓性皮炎病史的46岁女性，她在感染COVID-19后出现了快速进展的心力衰竭。她的心内膜心肌活检标本的病理检查结果与巨细胞性心肌炎（GCM）相符，并且通过联合免疫抑制治疗方案成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89c/9361461/d93d148250d9/CCR3-10-e6196-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89c/9361461/8f89e0c4b133/CCR3-10-e6196-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89c/9361461/f48bc35b217b/CCR3-10-e6196-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89c/9361461/d93d148250d9/CCR3-10-e6196-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89c/9361461/8f89e0c4b133/CCR3-10-e6196-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89c/9361461/f48bc35b217b/CCR3-10-e6196-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89c/9361461/d93d148250d9/CCR3-10-e6196-g001.jpg

相似文献

1
Giant cell myocarditis following COVID-19 successfully treated by immunosuppressive therapy.新冠病毒感染后巨细胞性心肌炎经免疫抑制治疗成功治愈
Clin Case Rep. 2022 Aug 9;10(8):e6196. doi: 10.1002/ccr3.6196. eCollection 2022 Aug.
2
Serial right ventricular endomyocardial biopsy in rapid-onset severe heart failure due to giant cell myocarditis.巨细胞性心肌炎所致快速进展性严重心力衰竭的系列右心室心内膜心肌活检
Cardiovasc Pathol. 2006 Jul-Aug;15(4):228-30. doi: 10.1016/j.carpath.2006.03.005.
3
A case report of giant cell myocarditis complicated by severe heart failure: the value of early endomyocardial biopsy and mechanical circulatory support.巨细胞性心肌炎合并严重心力衰竭的病例报告：早期心内膜心肌活检及机械循环支持的价值
Cardiovasc Diagn Ther. 2023 Dec 15;13(6):1136-1146. doi: 10.21037/cdt-23-265. Epub 2023 Nov 10.
4
Giant cell myocarditis attributable to myositis: therapeutic management under the guidance of serial endomyocardial biopsy-a case report.肌炎所致巨细胞性心肌炎：经皮心内膜心肌活检引导下的治疗管理——病例报告
Eur Heart J Case Rep. 2024 Jul 10;8(7):ytae326. doi: 10.1093/ehjcr/ytae326. eCollection 2024 Jul.
5
Cardiac sarcoidosis and giant cell myocarditis after COVID-19 infection.COVID-19 感染后的心肌肉样瘤病和巨细胞心肌炎。
ESC Heart Fail. 2022 Dec;9(6):4298-4303. doi: 10.1002/ehf2.14088. Epub 2022 Aug 22.
6
The role of right ventricular endomyocardial biopsy for idiopathic giant cell myocarditis.右心室心内膜活检在特发性巨细胞性心肌炎中的作用
J Card Fail. 2002 Apr;8(2):74-8. doi: 10.1054/jcaf.2002.32196.
7
A case of giant cell myocarditis mimicking cardiac sarcoidosis successfully maintained by prednisolone and tacrolimus.一例疑似心脏结节病的巨细胞性心肌炎患者，通过泼尼松龙和他克莫司成功维持治疗。
J Cardiol Cases. 2023 Feb 17;27(6):258-261. doi: 10.1016/j.jccase.2023.01.009. eCollection 2023 Jun.
8
Giant cell myocarditis in an older patient - reassessing the threshold for endomyocardial biopsy.老年患者的巨细胞性心肌炎——重新评估心内膜心肌活检的阈值
ESC Heart Fail. 2020 Oct;7(5):3165-3168. doi: 10.1002/ehf2.12756. Epub 2020 Jul 9.
9
Recurrent giant cell myocarditis following orthotopic heart transplant resulting in urgent redo orthotopic heart transplantation: a case report.原位心脏移植后复发性巨细胞性心肌炎导致紧急再次原位心脏移植：一例报告
Eur Heart J Case Rep. 2023 Nov 27;7(12):ytad602. doi: 10.1093/ehjcr/ytad602. eCollection 2023 Dec.
10
Fulminant Giant Cell Myocarditis following Heterologous Vaccination of ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19.接种ChAdOx1 nCoV-19和辉瑞-BioNTech新冠疫苗后发生的暴发性巨细胞心肌炎
Medicina (Kaunas). 2022 Mar 20;58(3):449. doi: 10.3390/medicina58030449.

引用本文的文献

1
Post-COVID-19 Femoral Head Osteonecrosis Exhibits Mast Cell Clusters, Fibrosis, and Vascular Thrombosis: Key Pathological Mechanisms in Long COVID-19 Bone Degeneration.新冠后股骨头坏死表现为肥大细胞簇、纤维化和血管血栓形成：长期新冠骨退变的关键病理机制
Pathophysiology. 2025 Jul 18;32(3):36. doi: 10.3390/pathophysiology32030036.
2
Post SARS-CoV-2 Myocarditis: Giant Cell or MIS-A? A Misdiagnosis Leading to a Heart Transplantation.新冠病毒感染后心肌炎：巨细胞性心肌炎还是多系统炎症综合征？一例导致心脏移植的误诊病例
JACC Case Rep. 2025 May 28;30(12):103514. doi: 10.1016/j.jaccas.2025.103514.
3
Immunomodulatory Therapy for Giant Cell Myocarditis: A Narrative Review.

本文引用的文献

1
Radiological-pathological signatures of patients with COVID-19-related pneumomediastinum: is there a role for the Sonic hedgehog and Wnt5a pathways?新型冠状病毒肺炎相关纵隔气肿患者的放射学-病理学特征：音猬因子和Wnt5a信号通路是否起作用？
ERJ Open Res. 2021 Aug 23;7(3). doi: 10.1183/23120541.00346-2021. eCollection 2021 Jul.
2
Myocarditis and Pericarditis After Vaccination for COVID-19.接种 COVID-19 疫苗后的心肌炎和心包炎。
JAMA. 2021 Sep 28;326(12):1210-1212. doi: 10.1001/jama.2021.13443.
3
Myocarditis and pericarditis after vaccination for COVID-19.
巨细胞性心肌炎的免疫调节治疗：一项叙述性综述。
Cureus. 2023 Jun 14;15(6):e40439. doi: 10.7759/cureus.40439. eCollection 2023 Jun.
新型冠状病毒肺炎疫苗接种后的心肌炎和心包炎
J Am Coll Emerg Physicians Open. 2021 Jul 26;2(4):e12498. doi: 10.1002/emp2.12498. eCollection 2021 Aug.
4
Progressive chronic SARS-CoV-2-positive giant cell myoendocarditis with atrial standstill and sudden cardiac death.进展性慢性 SARS-CoV-2 阳性巨细胞肌心内膜炎伴房性静止和心源性猝死。
ESC Heart Fail. 2021 Oct;8(5):4296-4300. doi: 10.1002/ehf2.13520. Epub 2021 Jul 29.
5
Comparison of the cardiovascular presentations, complications and outcomes following different coronaviruses' infection: A systematic review.不同冠状病毒感染后的心血管表现、并发症及结局比较：一项系统综述
J Cardiovasc Thorac Res. 2021;13(2):92-101. doi: 10.34172/jcvtr.2021.29. Epub 2021 Apr 24.
6
Myocarditis associated with Covid-19 disease: A systematic review of published case reports and case series.与 COVID-19 相关的心肌炎：已发表病例报告和病例系列的系统评价。
Int J Clin Pract. 2021 Nov;75(11):e14470. doi: 10.1111/ijcp.14470. Epub 2021 Jul 7.
7
Fulminant cardiac sarcoidosis resembling giant cell myocarditis: a case report.酷似巨细胞心肌炎的暴发性心脏结节病：一例报告
Eur Heart J Case Rep. 2021 Mar 10;5(3):ytab042. doi: 10.1093/ehjcr/ytab042. eCollection 2021 Mar.
8
Cardiac Sarcoidosis and Giant Cell Myocarditis: Actually, 2 Ends of the Same Disease?心脏结节病与巨细胞性心肌炎：实际上，是同一种疾病的两个极端？
J Am Heart Assoc. 2021 Mar 16;10(6):e020542. doi: 10.1161/JAHA.121.020542. Epub 2021 Mar 4.
9
Manifestations and Outcome of Cardiac Sarcoidosis and Idiopathic Giant Cell Myocarditis by 25-Year Nationwide Cohorts.25 年全国队列研究：心肌结节病和特发性巨细胞心肌炎的临床表现和转归。
J Am Heart Assoc. 2021 Mar 16;10(6):e019415. doi: 10.1161/JAHA.120.019415. Epub 2021 Mar 4.
10
Management of Patients With Giant Cell Myocarditis: JACC Review Topic of the Week.巨细胞心肌炎患者的管理：JACC 本周综述主题。
J Am Coll Cardiol. 2021 Mar 2;77(8):1122-1134. doi: 10.1016/j.jacc.2020.11.074.