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新冠病毒感染后巨细胞性心肌炎经免疫抑制治疗成功治愈

Giant cell myocarditis following COVID-19 successfully treated by immunosuppressive therapy.

作者信息

Amiri Afsaneh, Houshmand Golnaz, Taghavi Sepideh, Kamali Monireh, Faraji Mona, Naderi Nasim

机构信息

Rajaie Cardiovascular Medical and Research Center School of medicine, Iran University of Medical Sciences Tehran Iran.

出版信息

Clin Case Rep. 2022 Aug 9;10(8):e6196. doi: 10.1002/ccr3.6196. eCollection 2022 Aug.

Abstract

It has been shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), by coronavirus disease 2019 (COVID-19), can lead to multi-organ impairment including cardiac involvement and immunological problems. Acute myocarditis is one of serious and fatal complications of COVID-19. In this case report, we present a 46-year-old lady with a history of lichen planus dermatitis who has developed a rapidly progressive heart failure after an episode of COVID-19. The pathologic examination of her endomyocardial biopsy specimens was compatible with GCM, and she was successfully treated with a combined immunosuppressive therapy regimen.

摘要

已有研究表明,2019冠状病毒病(COVID-19)的致病源严重急性呼吸综合征冠状病毒2(SARS-CoV-2)可导致多器官损害,包括心脏受累和免疫问题。急性心肌炎是COVID-19严重且致命的并发症之一。在本病例报告中,我们介绍了一位有扁平苔藓性皮炎病史的46岁女性,她在感染COVID-19后出现了快速进展的心力衰竭。她的心内膜心肌活检标本的病理检查结果与巨细胞性心肌炎(GCM)相符,并且通过联合免疫抑制治疗方案成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89c/9361461/8f89e0c4b133/CCR3-10-e6196-g004.jpg

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