Ayati Aryan, Hosseini Kaveh, Hadizadeh Alireza, Jalali Arash, Lotfi-Tokaldany Masoumeh, Milan Nesa, Bagheri Jamshid, Ahmadi Tafti Seyed Hossein
Tehran Heart Center Research Institute, Tehran Heart Center Tehran University of Medical Sciences Tehran Iran.
Research Center for Advanced Technologies in Cardiovascular Medicine, Tehran Heart Center Tehran University of Medical Sciences Tehran Iran.
Health Sci Rep. 2022 Aug 10;5(5):e751. doi: 10.1002/hsr2.751. eCollection 2022 Sep.
Coronary artery disease is high-risk comorbidity of COVID-19 infection. Nonelective coronary artery revascularization in COVID-19 patients carries substantial risk. Therefore, it is essential to understand the risk factors and outcomes fully. This study aims to evaluate the prognosis of coronary artery bypass grafting (CABG) surgery in patients with COVID-19.
This retrospective cohort study assesses 171 patients who underwent urgent and emergent CABG in Tehran Heart Center from March 2020 to September 2021. The patients were allocated to cases and controls based on COVID-19 infection status. Demographic and clinical features, alongside the complications and outcomes, were compared between the two groups.
According to diagnostic criteria, 62 patients were diagnosed with COVID-19 (Case) and 109 patients had no COVID diagnosis (Control). Regarding the demographics and risk factors, hypertension was more prevalent among patients with COVID-19 (64.5% compared to 43.1% = 0.007). Length of hospital stay, ventilation time, and intensive care unit (ICU) stay time were significantly higher in patients infected with COVID-19. Postoperative complications, including stroke, atrial fibrillation, pleural effusion, blood transfusion, and Inotrope use, were significantly higher in the case group. Mortality rates were also higher in COVID-19 patients with an odds ratio of 1.53; however, this difference is not statistically significant (: 0.44, 95% CI = 0.50-4.01).
COVID-19 is associated with a significantly higher hospital stay, ventilation time, and ICU stay. Mortality rates are also higher, albeit insignificantly. Various postoperative complications are also higher with COVID-19.
冠状动脉疾病是新冠病毒感染的高风险合并症。新冠病毒感染患者进行非选择性冠状动脉血运重建手术风险极大。因此，全面了解风险因素及预后情况至关重要。本研究旨在评估新冠病毒感染患者接受冠状动脉旁路移植术（CABG）的预后。
这项回顾性队列研究评估了2020年3月至2021年9月在德黑兰心脏中心接受紧急和急诊冠状动脉旁路移植术的171例患者。根据新冠病毒感染状况将患者分为病例组和对照组。比较两组的人口统计学和临床特征以及并发症和预后情况。
根据诊断标准，62例患者被诊断为新冠病毒感染（病例组），109例患者未被诊断为新冠病毒感染（对照组）。在人口统计学和风险因素方面，高血压在新冠病毒感染患者中更为普遍（64.5% 对比43.1%，P = 0.007）。新冠病毒感染患者的住院时间、通气时间和重症监护病房（ICU）停留时间显著更长。病例组的术后并发症，包括中风、房颤、胸腔积液、输血和使用血管活性药物的比例显著更高。新冠病毒感染患者的死亡率也更高，比值比为1.53；然而，这种差异无统计学意义（P = 0.44，95%置信区间 = 0.50 - 4.01）。
新冠病毒感染与显著更长的住院时间、通气时间和ICU停留时间相关。死亡率也更高，尽管无统计学意义。新冠病毒感染患者的各种术后并发症也更多。
