Dibeklioğlu Saime Ergen, Baş Veysel Nijat, Yalınbaş Emine Esin, Umay Sermin Tok
Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey.
Kutahya Health Sciences University Medical Faculty, Kutahya, Turkey.
Sudan J Paediatr. 2022;22(1):98-103. doi: 10.24911/SJP.106-1602681630.
Subcutaneous fat necrosis (SCFN) is an uncommon cause of neonatal hypercalcaemia. It is usually seen in neonates after a complicated delivery within the first month of life. While uncommon, hypercalcaemia can be fatal. It is characterised by red-purple plaques in fatty points along with firm subcutaneous nodules. Rarely, SCFN may cause severe hypercalcaemia with no visible skin lesion. In this rare case, we report severe infancy hypercalcaemia without characteristic skin lesion on first physical examination, unresponsive to hydration, diuretic, prednisolone and standard dose of pamidronate treatment. As timely diagnosis and treatment are so important, this complication should be kept in mind even in such clinical presentations.
皮下脂肪坏死（SCFN）是新生儿高钙血症的一种罕见病因。它通常见于出生后第一个月内经历复杂分娩的新生儿。虽然罕见，但高钙血症可能是致命的。其特征为脂肪部位出现红紫色斑块以及坚实的皮下结节。极少数情况下，皮下脂肪坏死可能导致严重高钙血症且无可见皮肤病变。在这个罕见病例中，我们报告了一例严重婴儿期高钙血症，首次体格检查时无特征性皮肤病变，对补液、利尿剂、泼尼松龙和标准剂量的帕米膦酸治疗均无反应。由于及时诊断和治疗非常重要，即使在这种临床表现中也应牢记这种并发症。
