Zhou Jupu, Su Peng, Zhao Jiaju, Zuo Zhicheng, Zhu Zhenhua, Zhou Kailong
Department of Hand and Foot Surgery, The Second Affiliated Hospital of Soochow University Suzhou 215004, Jiangsu, China.
Department of Orthopedics, The Second Affiliated Hospital of Soochow University Suzhou 215004, Jiangsu, China.
Am J Transl Res. 2022 Jul 15;14(7):5068-5076. eCollection 2022.
This study aimed to investigate the effect of arterial blood supply on the survival area of retrograde island flap.
The vein and saphenous artery in rabbits were selected to design the reverse-flow island flap experimental model. Forty rabbits were randomly divided into four groups: control group (group A), partial anastomosis of the saphenous artery group (group B), partial anastomosis of the vein group (group C), and no superficial vein group (group D). Flap survival was observed postoperatively, the survival area was measured, and the survival rate was compared. Blood distribution in the flap at different time points was observed by radionuclide imaging.
The blood vessel distribution and blood cell status were observed histologically. The survival rate of flaps in group B was higher than that of the other three groups (P < 0.05). The radioactive material (RM) could be seen clearly in group B, whereas those in groups A, C, and D existed transiently. The RM in group B was higher than that in groups A, C, and D (P < 0.05). On postoperative day 10, group B had more capillary regeneration and blood cells than the other three groups (P < 0.05).
Increasing blood supply can improve the survival rate of flaps, but simply promoting venous return has no significant effect on the survival rate of flaps.
本研究旨在探讨动脉血供对逆行岛状皮瓣存活面积的影响。
选取兔的静脉及隐动脉设计反流岛状皮瓣实验模型。40只兔随机分为4组：对照组（A组）、隐动脉部分吻合组（B组）、静脉部分吻合组（C组）、无浅静脉组（D组）。术后观察皮瓣存活情况，测量存活面积并比较存活率。通过放射性核素显像观察不同时间点皮瓣内的血液分布情况。
组织学观察血管分布及血细胞状态。B组皮瓣存活率高于其他三组（P<0.05）。B组放射性物质（RM）显影清晰，而A、C、D组为一过性显影。B组RM高于A、C、D组（P<0.05）。术后第10天，B组毛细血管再生及血细胞数量多于其他三组（P<0.05）。
增加血供可提高皮瓣存活率，但单纯促进静脉回流对皮瓣存活率无显著影响。
