Tanaka Y, Tajima S
Department of Plastic and Reconstructive Surgery, Osaka Medical College, Japan.
Plast Reconstr Surg. 1997 Jun;99(7):2021-9. doi: 10.1097/00006534-199706000-00031.
Reversed-flow flaps are currently used for reconstruction of the distal portion of the upper and lower extremities. However, detailed experimental studies on the reversed-flow flap are lacking, and there have been many clinical reports concerning its postoperative complications. In the present study, the effects of blood inflow and outflow on flap viability were investigated. Six groups of island flaps, which differed in whether arterial inflow and venous outflow were retrograde or antegrade, were prepared on the rat's abdomen. The venous pressure of the vascular pedicle (n = 5), the blood flow (n = 10), and the survival rates of flaps (n = 10) were measured in each group. When arterial inflow was retrograde, the viable flap area diminished in proportion to the decrease in blood flow. The correlation coefficient between blood flow and survival rates of the flaps was 0.885, which indicates that blood inflow to the flap is closely related to the area of flap viability. The relationship between the venous outflow and the viable flap area was "all or nothing". When venous outflow was retrograde, there was either no effect on flap area at all or complete congestive necrosis.
逆流皮瓣目前用于上下肢远端的重建。然而，关于逆流皮瓣的详细实验研究尚缺乏，且有许多关于其术后并发症的临床报告。在本研究中，研究了血液流入和流出对皮瓣存活能力的影响。在大鼠腹部制备了六组岛状皮瓣，每组皮瓣的动脉流入和静脉流出是逆行还是顺行有所不同。测量每组血管蒂的静脉压力（n = 5）、血流量（n = 10）和皮瓣存活率（n = 10）。当动脉流入为逆行时，存活的皮瓣面积随血流量的减少而成比例减小。皮瓣血流量与存活率之间的相关系数为0.885，这表明皮瓣的血液流入与皮瓣存活面积密切相关。静脉流出与存活皮瓣面积之间的关系是“全或无”。当静脉流出为逆行时，要么对皮瓣面积完全没有影响，要么完全充血坏死。
