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青少年不良经历模式与青年成人抑郁症状轨迹:中国大学生的一项纵向研究。

Patterns of adverse childhood experiences and depressive symptom trajectories in young adults: A longitudinal study of college students in China.

作者信息

Li Shuqin, Wang Rui, Thomas Erica, Jiang Zhicheng, Jin Zhengge, Li Ruoyu, Qian Yan, Song Xianbing, Sun Ying, Zhang Shichen, Chen Ruoling, Wan Yuhui

机构信息

Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Anhui, China.

Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui, China.

出版信息

Front Psychiatry. 2022 Jul 25;13:918092. doi: 10.3389/fpsyt.2022.918092. eCollection 2022.

Abstract

BACKGROUND

Adverse childhood experiences (ACEs) tend to cluster together in daily life, and most studies focus on the level of depression at certain points, but the dynamic process of depression is often neglected. Thus, research is urgently needed to explore the relationship between ACEs pattern and trajectory of depressive symptom levels at multiple time points in order to provides early targeted interventions to those who are most at risk.

OBJECTIVE

We aimed to explore patterns of ACEs, including types and timing, associated with depression trajectories in college students.

METHODS

A school-based health survey was used to collect data as part of a longitudinal study in two medical college in Anhui province, China. Questionnaires were issued to 3,662 participants aged 17-22 and recorded details of ACEs (types and timing) and depression. Latent class analysis (LCA) was used to identify "patterns" of ACEs type and timing. Depressive symptom trajectories employed latent class growth analysis (LCGA). Multiple logistic regressions were employed to evaluate the relationships between ACEs patterns and depressive symptom trajectories.

RESULTS

We identified five ACEs patterns: "High neglect/emotional abuse/community violence," "High neglect/emotional abuse," "High neglect/family dysfunction," "High neglect," "Low ACEs." We traced three depression trajectories: "High depressive symptom" "Moderate depressive symptom," "Low depressive symptom." "High neglect/emotional abuse/community violence," "High neglect/emotional abuse" and "High neglect/family dysfunction" demonstrated a high risk for "High depressive symptom" and "Moderate depressive symptom." "High neglect" showed a high risk for "Moderate depressive symptom" but not for "High depressive symptom" ( < 0.05).

CONCLUSIONS

The findings address the need for a comprehensive consideration of exposure to childhood adversity associated with the risk of depression in young adults through identifying more problematic ACEs patterns amongst exposed children.

摘要

背景

童年不良经历(ACEs)在日常生活中往往聚集在一起,大多数研究关注特定时间点的抑郁水平,但抑郁的动态过程常常被忽视。因此,迫切需要开展研究,以探索ACEs模式与多个时间点抑郁症状水平轨迹之间的关系,从而为最具风险的人群提供早期针对性干预措施。

目的

我们旨在探索与大学生抑郁轨迹相关的ACEs模式,包括类型和时间。

方法

作为中国安徽省两所医学院校纵向研究的一部分,采用基于学校的健康调查收集数据。向3662名年龄在17 - 22岁的参与者发放问卷,记录ACEs(类型和时间)及抑郁的详细信息。使用潜在类别分析(LCA)来识别ACEs类型和时间的“模式”。采用潜在类别增长分析(LCGA)研究抑郁症状轨迹。运用多重逻辑回归评估ACEs模式与抑郁症状轨迹之间的关系。

结果

我们识别出五种ACEs模式:“高忽视/情感虐待/社区暴力”、“高忽视/情感虐待”、“高忽视/家庭功能障碍”、“高忽视”、“低ACEs”。我们追踪到三种抑郁轨迹:“高抑郁症状”“中度抑郁症状”“低抑郁症状”。“高忽视/情感虐待/社区暴力”、“高忽视/情感虐待”和“高忽视/家庭功能障碍”表现出出现“高抑郁症状”和“中度抑郁症状”的高风险。“高忽视”表现出出现“中度抑郁症状”的高风险,但未表现出出现“高抑郁症状”的高风险(<0.05)。

结论

研究结果表明,有必要通过识别受暴露儿童中更具问题的ACEs模式,全面考虑与年轻人抑郁风险相关的童年逆境暴露情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/425b/9358020/ef4e390f87ae/fpsyt-13-918092-g0001.jpg

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