Zhao Lei, Xiu Shuangling, Sun Lina, Mu Zhijing, Fu Junling
Department of Endocrinology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Department of Geriatrics, Capital Medical University, Beijing, China.
Evid Based Complement Alternat Med. 2022 Aug 1;2022:9041551. doi: 10.1155/2022/9041551. eCollection 2022.
The objective of this study was to examine the correlation between blood glucose and serum insulin with acute cerebrovascular disease.
A total of 1548 patients with acute cerebrovascular illness and 364 patients with a normal physical examination who were admitted to our hospital (endocrinology department) between January 2017 and July 2020 were recruited. Patients with acute cerebrovascular illness were included in the experimental group, while healthy individuals after physical examinations were included in the control group. All patients' blood glucose and serum insulin levels were measured, and the association of blood glucose and serum insulin with acute cerebrovascular illness was investigated.
Acute cerebrovascular disease is associated with significantly higher blood glucose and serum insulin levels versus healthy status ( < 0.05). Blood glucose and serum insulin levels were observed to be significantly higher in the hemorrhagic stroke group than in the ischemic stroke or mild hemorrhagic group ( < 0.05). Severe ischemic strokes were associated with significantly higher blood glucose levels versus mild ischemic strokes ( < 0.05). There were no significant differences in serum insulin levels between the severe ischemic stroke group and the mild ischemic stroke group ( > 0.05).
A rise in blood glucose and serum insulin levels is associated with the incidence and prognosis of acute cerebrovascular disease, and it is positively correlated with the severity of the acute cerebrovascular disease.
本研究旨在探讨血糖和血清胰岛素与急性脑血管疾病之间的相关性。
选取2017年1月至2020年7月期间我院（内分泌科）收治的1548例急性脑血管疾病患者和364例体检正常者。急性脑血管疾病患者纳入实验组，体检后的健康个体纳入对照组。测量所有患者的血糖和血清胰岛素水平，并研究血糖和血清胰岛素与急性脑血管疾病的关联。
与健康状态相比，急性脑血管疾病患者的血糖和血清胰岛素水平显著更高（<0.05）。出血性卒中组的血糖和血清胰岛素水平显著高于缺血性卒中组或轻度出血组（<0.05）。重度缺血性卒中患者的血糖水平显著高于轻度缺血性卒中患者（<0.05）。重度缺血性卒中组和轻度缺血性卒中组的血清胰岛素水平无显著差异（>0.05）。
血糖和血清胰岛素水平的升高与急性脑血管疾病的发生和预后相关，且与急性脑血管疾病的严重程度呈正相关。
