Sawada T
Dev Biol Stand. 1986;58 ( Pt A):145-8.
The disposable unit-dose BCG vaccine for multipuncture has some advantages in that the vaccination can be performed immediately without arrangements even by laymen, anytime, anywhere when needed, with no chance of contamination as hepatitis infection. No decrease of potency at vaccination, and no wastage of vaccine was observed. This vaccine showed the stability of potency the same as multi-dose vaccine. The tuberculin conversion rates and local lesions induced by this vaccine on babies and infants were observed to be the same as the multi-dose vaccine.
一次性单剂量多针刺卡介苗具有一些优点,即无需事先安排,即使是外行人员也可在需要时随时随地立即进行接种,不存在如肝炎感染那样的污染风险。接种时未观察到效力降低,也未出现疫苗浪费的情况。该疫苗显示出与多剂量疫苗相同的效力稳定性。观察发现,这种疫苗在婴幼儿身上引起的结核菌素转化率和局部病变与多剂量疫苗相同。