蚊子中的遗传工具方法。
Genetic Toolbox Approaches in Mosquitoes.
机构信息
Department of Biosciences, Durham University, Durham, DH1 3LE, United Kingdom
Department of Biosciences, Durham University, Durham, DH1 3LE, United Kingdom.
出版信息
Cold Spring Harb Protoc. 2022 Nov 1;2022(11):Pdb.top107691. doi: 10.1101/pdb.top107691.
PMID:35960628
Abstract
Mosquitoes are fascinating and diverse study organisms that are rapidly becoming genetically tractable. Here, we review the latest and most commonly used approaches to silence or edit genes and express transgenes in mosquitoes. We also focus on gene drives-a genetic technology that may prove essential for combating mosquito-borne diseases.
摘要
蚊子是一种迷人且多样的研究生物，它们正迅速变得具有遗传操作性。在这里，我们回顾了最新和最常用的沉默或编辑基因以及在蚊子中表达转基因的方法。我们还重点介绍了基因驱动——一种可能对防治蚊媒疾病至关重要的遗传技术。
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