犬胫骨平台水平截骨术采用抗菌银涂层板的长期疗效。

Long-term outcome of tibial plateau leveling osteotomy using an antimicrobial silver-based coated plate in dogs.

机构信息

Surgery Department, Centre Hospitalier Vétérinaire Aquivet, Eysines, France.

出版信息

PLoS One. 2022 Aug 12;17(8):e0272555. doi: 10.1371/journal.pone.0272555. eCollection 2022.

DOI:10.1371/journal.pone.0272555

PMID:35960740

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9374240/

Abstract

OBJECTIVES

To evaluate long-term outcome using the BioMedtrix™ TPLO Curve® plate in dogs with cranial cruciate ligament disease (CrCLd) treated by tibial plateau leveling osteotomy (TPLO).

STUDY DESIGN

Retrospective case study.

ANIMALS

Dogs (n = 323, 337 stifles).

METHODS

Medical records were searched for dogs presented with CrCLd and treated by TPLO with the BioMedtrix™ TPLO Curve® plate for 3.5 mm screws between March 2018 and December 2020. Tibial plateau angles (TPA) were measured on preoperative, postoperative, and follow-up radiographs. Changes in TPA between postoperative and follow-up radiographs (ModTPA) were calculated. Radiographic bone healing was scored. Complications were evaluated. Surgical site infections (SSI) were compared to a control group of dogs treated with the Synthes™ TPLO plate between January and December 2017. Owners of both groups were contacted by telephone at least 1 year postoperatively.

RESULTS

The BioMedtrix™ group was composed of 237 dogs (248 stifles), the control group was composed of 86 dogs (89 stifles). In the BioMedtrix™ group, radiographic follow-up was performed at a median of 48 days. Average ModTPA was 1.2°. Bone healing was graded as complete, good, poor, and none in 18%, 62%, 20%, and 0%, respectively. At a median of 786 days postoperatively, minor and major postoperative complications were observed in 6 (2.4%) and 32 (12.9%) cases in this group, respectively. During the first year following the surgery, 23 (9.3%) and 12 (13.5%) cases suffered a SSI, of which 12 (4.8%) and 7 (7.9%) had their implant explanted in the BioMedtrix™ group and the control group, respectively. There was no significant difference between groups for SSI and implant explantations (p = 0.31 and p = 0.29, respectively).

CONCLUSION

The BioMedtrix™ TPLO Curve® plate provided a reliable fixation system for osteotomy healing after TPLO. Bone healing and long-term complication rates were similar to previous studies using other implants. SSI rates were similar between the BioMedtrix™ group and the control group. The antimicrobial HyProtect® coating of the plate did not reduce SSI in this study.

CLINICAL SIGNIFICANCE

The BioMedtrix™ TPLO Curve® plate can be safely used for TPLO. The value of the antimicrobial HyProtect® coating of the plate may be questioned, as SSI rate was not lower in this study compared to the control group or previous reports.

摘要

目的

评估使用 BioMedtrix™ TPLO Curve®板治疗前十字韧带断裂（CrCLd）的犬胫骨平台抬高截骨术（TPLO）的长期结果。

研究设计

回顾性病例研究。

动物

狗（n = 323，337 个膝关节）。

方法

检索 2018 年 3 月至 2020 年 12 月间因 CrCLd 接受 BioMedtrix™ TPLO Curve®板治疗的犬的医疗记录。术前、术后和随访 X 线片上测量胫骨平台角度（TPA）。计算术后和随访 X 线片之间 TPA 的变化（ModTPA）。对 X 线片骨愈合进行评分。评估并发症。比较 2017 年 1 月至 12 月接受 Synthes™ TPLO 板治疗的对照组的手术部位感染（SSI）。两组的主人在术后至少 1 年通过电话联系。

结果

BioMedtrix™组由 237 只狗（248 个膝关节）组成，对照组由 86 只狗（89 个膝关节）组成。在 BioMedtrix™组中，术后 X 线片随访中位数为 48 天。平均 ModTPA 为 1.2°。骨愈合分别评为完全、良好、差和无愈合，分别为 18%、62%、20%和 0%。术后中位数 786 天，该组分别有 6 例（2.4%）和 32 例（12.9%）出现轻微和严重的术后并发症。在术后第一年，BioMedtrix™组和对照组分别有 23 例（9.3%）和 12 例（13.5%）发生 SSI，其中 BioMedtrix™组和对照组分别有 12 例（4.8%）和 7 例（7.9%）的植入物被取出。两组 SSI 和植入物取出的发生率无统计学差异（p = 0.31 和 p = 0.29）。