Giannetto Jessica J, Aktay Sevima A
Virginia Veterinary Surgical Associates, a BluePearl Partner, Richmond, Virginia, United States.
Vet Comp Orthop Traumatol. 2019 Jan;32(1):18-25. doi: 10.1055/s-0038-1676352. Epub 2019 Jan 15.
The main aim of this study was to evaluate the efficacy of a topical 2-octyl cyanoacrylate (2OC) tissue adhesive and an adhesive barrier dressing (BD) in minimizing the incidence of surgical site infections (SSI) in dogs undergoing a tibial plateau levelling osteotomy (TPLO).
In a prospective clinical study, 437 client-owned dogs undergoing a TPLO as treatment for cranial cruciate ligament disease with or without concurrent patellar luxations from July 2015 to September 2016 were included. In each dog, the type of postoperative wound dressing was randomly selected as either no dressing (ND), a 2OC tissue adhesive or an adhesive BD. Direct examination by a veterinarian was performed at 14, 30, 60 and 90 days postoperatively. If dogs did not return for direct examination, owners were contacted with a questionnaire for the final follow-up of at least 90 days.
The overall rate of SSI was 2.3% (10/437). Methicillin-resistant was the most common bacteria isolated in 9/10 cases. Infection was confirmed in 2.76% (4/145) of dogs with ND, 2.01% (3/149) of dogs with 2OC and 2.10% (3/143) of dogs with BD. Of the dogs that developed an SSI, type of dressing was not a significant risk factor ( = 0.5305) for infection. Increasing body weight was the only significant risk factor that increased the risk of overall infection (odds ratio = 1.03 [95% confidence interval: 1.02-1.05]).
In dogs undergoing a TPLO, there may be no clear benefit in the usage of postoperative wound dressings for the prevention of SSI. Increasing body weight was the only significant factor associated with the development of an SSI.
本研究的主要目的是评估局部应用2-辛基氰基丙烯酸酯(2OC)组织粘合剂和粘性屏障敷料(BD)对接受胫骨平台水平截骨术(TPLO)的犬手术部位感染(SSI)发生率的影响。
在一项前瞻性临床研究中,纳入了2015年7月至2016年9月期间437只接受TPLO治疗颅交叉韧带疾病且伴有或不伴有髌骨脱位的客户自养犬。每只犬的术后伤口敷料类型随机选择为不使用敷料(ND)、2OC组织粘合剂或粘性BD。术后14、30、60和90天由兽医进行直接检查。如果犬未返回进行直接检查,则通过问卷与主人联系进行至少90天的最终随访。
SSI的总体发生率为2.3%(10/437)。耐甲氧西林菌是10例中9例分离出的最常见细菌。ND组犬的感染确诊率为2.76%(4/145),2OC组为2.01%(3/149),BD组为2.10%(3/143)。在发生SSI的犬中,敷料类型不是感染的显著危险因素(=0.5305)。体重增加是增加总体感染风险的唯一显著危险因素(优势比=1.03[95%置信区间:1.02-1.05])。
在接受TPLO的犬中,使用术后伤口敷料预防SSI可能没有明显益处。体重增加是与SSI发生相关的唯一显著因素。