Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina. Drs. Pona, Cardenas-de la Garza, Broderick, and Bowers are from the Center for Dermatology Research. Drs. Sanguenza and Niehuas also are from the Department of Dermatology. Dr. Pona also is from the Department of Internal Medicine, Vidant Medical Center/East Carolina University, Greenville, North Carolina. Dr. Cardenas-de la Garza also is from the Department of Dermatology, Universidad Autónoma de Nuevo León, Hospital Universitario Dr. José E. González, Monterrey, México.
Cutis. 2022 Jun;109(6):330-332. doi: 10.12788/cutis.0544.
Lupus erythematosus tumidus (LET) is a rare photosensitive der-matosis that was considered a subtype of chronic cutaneous lupus erythematosus (CLE); however, its clinical course and favorable prognosis led to its reclassification into another category called intermittent CLE. Although known for more than 100 years, LET's association with systemic lupus erythematosus (SLE), autoantibody profile, and disease prognosis is not well characterized. The purpose of this study was to describe the demographics, clinical characteristics, autoantibody profile, comorbidities, and treatment of LET.
红斑狼疮肿胀 (LET) 是一种罕见的光敏性皮炎,被认为是慢性皮肤红斑狼疮 (CLE) 的一种亚型;然而,其临床病程和良好的预后导致其重新分类为另一种称为间歇性 CLE。尽管已经有 100 多年的历史,但 LET 与系统性红斑狼疮 (SLE)、自身抗体谱和疾病预后的关系尚未得到很好的描述。本研究的目的是描述 LET 的人口统计学、临床特征、自身抗体谱、合并症和治疗。