Yu Yahan, Xiong Zhaokun, Huang Bingkun, Wang Xinhao, Du Ye, He Chuanshu, Liu Yang, Yao Gang, Lai Bo
State Key Laboratory of Hydraulics and Mountain River Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, China; Sino-German Centre for Water and Health Research, Sichuan University, Chengdu 610065, China; Yibin Institute of Industrial Technology, Sichuan University, Yibin, China.
State Key Laboratory of Hydraulics and Mountain River Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, China; Sino-German Centre for Water and Health Research, Sichuan University, Chengdu 610065, China; Yibin Institute of Industrial Technology, Sichuan University, Yibin, China; Water Safety and Water Pollution Control Engineering Technology Research Center in Sichuan Province, Haitian Water Group, China.
Environ Int. 2022 Oct;168:107453. doi: 10.1016/j.envint.2022.107453. Epub 2022 Aug 5.
Herein, a highly efficient electro-peroxone (E-peroxone) process with graphite felt as ozone diffusion electrode (ODE) was developed for the synchronous removal of pharmaceutical contaminants and inactivation of pathogenic microorganisms in real hospital wastewater. Under optimal conditions, the total organic carbon (TOC) removal rate of real hospital wastewater could reach 93.9%. Importantly, 126 pharmaceutical compounds (antibiotics, antivirals, analgesics, antiepileptics, hormones, and others) were determined in hospital wastewater by using ultra performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS/MS). 110 pharmaceutical compounds could be efficiently degraded in E-peroxone system. Concurrently, the microbial community analysis through high-throughput sequencing showed that E-peroxone process exhibited an excellent disinfection effect in real hospital wastewater. Escherichia coli as a bacterial indicator could be completely inactivated in E-peroxone process·HO and hydroxyl radical (OH) were found in E-peroxone system based on the results of chemical probe experiments and electron paramagnetic resonance (EPR) analysis. The in-situ generation of HO from cathodic oxygen reduction in ODE can react with ozone to produce OH, and realize high efficiencies for the elimination of pharmaceutical and sterilization. This work established a green and effective way without extra addition of chemical reagents for high-efficiency treatment of real hospital wastewater.
在此，开发了一种以石墨毡为臭氧扩散电极（ODE）的高效电-过氧单硫酸盐（E-过氧单硫酸盐）工艺，用于同步去除实际医院废水中的药物污染物和灭活致病微生物。在最佳条件下，实际医院废水的总有机碳（TOC）去除率可达93.9%。重要的是，采用超高效液相色谱结合四极杆飞行时间质谱（UPLC-Q-TOF-MS/MS）测定了医院废水中的126种药物化合物（抗生素、抗病毒药、镇痛药、抗癫痫药、激素等）。110种药物化合物在E-过氧单硫酸盐体系中可被有效降解。同时，通过高通量测序进行的微生物群落分析表明，E-过氧单硫酸盐工艺在实际医院废水中表现出优异的消毒效果。作为细菌指标的大肠杆菌在E-过氧单硫酸盐工艺中可被完全灭活。基于化学探针实验和电子顺磁共振（EPR）分析结果，在E-过氧单硫酸盐体系中发现了·HO和羟基自由基（OH）。ODE中阴极氧还原原位生成的·HO可与臭氧反应生成OH，实现药物消除和杀菌的高效性。这项工作建立了一种无需额外添加化学试剂的绿色有效方法，用于高效处理实际医院废水。
