Xiang Lingling, Wang Botao, Zhang Yuan, Wang Jintao, Wu Peipei, Zhang Jian, Zhong Liangjun, He Rui
School of Stomatology, Hangzhou Normal University, Hangzhou, 311121, China.
Department of Stomatology, Integrated Traditional and Western Medicine Hospital of Linping District, Hangzhou, 311100, China.
Odontology. 2023 Jan;111(1):248-254. doi: 10.1007/s10266-022-00733-5. Epub 2022 Aug 14.
Periodontitis has a known association with pathological calcification in the cardiovascular system. Considering the close anatomic and circulatory association between dental pulp and the periodontium, this study aimed to evaluate the prevalence of pulp calcification (PC) under different periodontal conditions, as well as the associations of PC with the degree of periodontal damage, via cone beam computed tomography (CBCT) examination. In this study, 55 patients were categorized into three groups according to periodontal condition: group 1 (healthy controls), group 2 (periodontitis stage I-II), and group 3 (periodontitis stage III-IV). PC and radiographic bone loss (RBL) was assessed by CBCT in sagittal, axial, and coronal views, and statistical analyses were conducted. PC was identified in 378 of 1170 teeth (32.3%). The prevalence significantly differed among the three groups (P < 0.001). Group 2 had a 2.43-fold (P < 0.001, 95% confidence interval [CI] 1.64-3.61) higher risk of PC than group 1; and the risk of PC was 3.04-fold (P < 0.001, 95% CI 2.06-4.48) higher in group 3 than group 1. Teeth with more severe RBL exhibited a higher prevalence of PC (P < 0.001). Molar teeth had a higher risk of PC than incisors and premolars. In conclusion, the occurrence of PC is related to the periodontal state, and the prevalence of PC is higher in teeth with periodontitis; tooth type and periodontitis status are important risk factors for PC.
牙周炎与心血管系统的病理性钙化存在已知关联。鉴于牙髓与牙周组织在解剖和循环方面联系紧密，本研究旨在通过锥形束计算机断层扫描（CBCT）检查，评估不同牙周状况下牙髓钙化（PC）的患病率，以及PC与牙周损伤程度之间的关联。在本研究中，55名患者根据牙周状况被分为三组：第1组（健康对照组）、第2组（牙周炎I - II期）和第3组（牙周炎III - IV期）。通过CBCT在矢状面、轴面和冠状面评估PC和影像学骨丧失（RBL），并进行统计分析。在1170颗牙齿中的378颗（32.3%）发现了PC。三组之间的患病率有显著差异（P < 0.001）。第2组发生PC的风险比第1组高2.43倍（P < 0.001，95%置信区间[CI] 1.64 - 3.61）；第3组发生PC的风险比第1组高3.04倍（P < 0.001，95% CI 2.06 - 4.48）。RBL越严重的牙齿，PC的患病率越高（P < 0.001）。磨牙发生PC的风险高于切牙和前磨牙。总之，PC的发生与牙周状态有关，牙周炎患牙中PC的患病率更高；牙齿类型和牙周炎状态是PC的重要危险因素。
