Hearing Research Unit for Children, Division of Audiology, School of Health & Rehabilitation Sciences, The University of Queensland, Brisbane, 4072, Australia; Children's Health Queensland Hospital and Health Service, Child and Youth Community Health Service, 10 Chapel Street, Nundah, Queensland, 4012, Australia.
Children's Health Queensland Hospital and Health Service, Child and Youth Community Health Service, 10 Chapel Street, Nundah, Queensland, 4012, Australia.
Int J Pediatr Otorhinolaryngol. 2022 Oct;161:111268. doi: 10.1016/j.ijporl.2022.111268. Epub 2022 Aug 5.
Universal Newborn Hearing Screening (UNHS) aims to identify infants born with a permanent hearing loss. However, many are also diagnosed with a conductive hearing loss (CHL) and are at subsequent risk for developmental delays. The aim of this study was to investigate the prevalence of CHL and determine which clinical characteristics collected at birth, predict CHL within UNHS.
Retrospective analysis was conducted on all infants born between January 01, 2007 and December 31, 2018. During this period, 731,234 infants were screened, 9802 were direct referrals, and 1208 identified with a CHL. Chi squared analysis and logistic regression was conducted to determine CHL prevalence and identify which clinical characteristics predict CHL.
The prevalence of CHL was 12.32%. Following adjustments for collinearity, clinical characteristics that could predict CHL were: bilateral referrals/medical exclusions to screen (Odds ratio, OR 1.89; 95% CI: 1.65-2.1), ≥1 risk factor for hearing loss (OR 2.03; 95% CI: 1.76-2.34), pre-term birth (OR 1.82; 95% CI: 1.57-2.10), male (OR 1.21; 95% CI: 1.07-1.37), and Indigenous status: 'Aboriginal (not Torres Strait Islander)' (OR 1.27; 95% CI:1.03-1.57 and 'not stated' (OR 2.95; 95% CI: 2.02-4.30).
CHL within UNHS was highly prevalent, with six clinical characteristics that can predict that likelihood of an infant being diagnosed with a CHL. This data could be used to create alternative care pathways for infants with CHL, enabling early and targeted assessments, thereby reducing the risk of developmental delays for these infants.
新生儿普遍听力筛查（UNHS）旨在发现出生时患有永久性听力损失的婴儿。然而，许多婴儿也被诊断为传导性听力损失（CHL），随后有发育迟缓的风险。本研究旨在调查 CHL 的患病率，并确定在 UNHS 期间出生时收集的哪些临床特征可预测 CHL。
对 2007 年 1 月 1 日至 2018 年 12 月 31 日期间出生的所有婴儿进行回顾性分析。在此期间，对 731234 名婴儿进行了筛查，9802 名婴儿直接转诊，1208 名婴儿被诊断为 CHL。进行卡方分析和逻辑回归以确定 CHL 的患病率，并确定哪些临床特征可预测 CHL。
CHL 的患病率为 12.32%。在校正共线性后，可预测 CHL 的临床特征为：双侧转诊/排除筛查的医学原因（优势比，OR 1.89；95%置信区间：1.65-2.1）、≥1 个听力损失危险因素（OR 2.03；95%置信区间：1.76-2.34）、早产（OR 1.82；95%置信区间：1.57-2.10）、男性（OR 1.21；95%置信区间：1.07-1.37）和原住民身份：“原住民（非托雷斯海峡岛民）”（OR 1.27；95%置信区间：1.03-1.57）和“未说明”（OR 2.95；95%置信区间：2.02-4.30）。
UNHS 中的 CHL 患病率很高，有 6 个临床特征可以预测婴儿被诊断为 CHL 的可能性。该数据可用于为患有 CHL 的婴儿创建替代护理途径，从而能够对这些婴儿进行早期和针对性评估，从而降低他们发育迟缓的风险。
