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从 10 年的普遍新生儿听力筛查结果和危险因素预测听力损失。

Predicting hearing loss from 10 years of universal newborn hearing screening results and risk factors.

机构信息

Healthy Hearing Program, Children's Health Queensland Hospital and Health Service, Brisbane, Australia.

School of Health and Rehabilitation Services, University of Queensland, Brisbane, Australia.

出版信息

Int J Audiol. 2021 Dec;60(12):1030-1038. doi: 10.1080/14992027.2021.1871975. Epub 2021 Feb 16.

DOI:10.1080/14992027.2021.1871975
PMID:33593173
Abstract

OBJECTIVE

This study investigated whether demographic variables, risk factor presence or absence and universal newborn hearing screening (UNHS) results can be used to predict permanent childhood hearing loss (PCHL) in infants referred from screening.

DESIGN

Retrospective analysis of a UNHS database.

STUDY SAMPLE

Data were extracted from the state-wide UNHS database storing details of the 613,027 infants who were born in Queensland, Australia between 1 January 2007 and 31 December 2016 and participated in UNHS. This study included the 6735 children who were referred from the UNHS program for diagnostic audiology due to failing the screen in one or both ears or bypassing screening.

RESULTS

Factors with a significant positive association with PCHL that were incorporated into a logistic regression model were: female gender, non-indigenous status, family history of PCHL, craniofacial anomalies and syndromes associated with PCHL, and a bilateral refer result on screening.

CONCLUSIONS

Odds of PCHL vary among infants referred for diagnostic assessment from UNHS programs. When an infant refers on the newborn hearing screen, information about their gender, indigenous status, identified risk factors and specific screening outcome can be used to predict the likelihood of a congenital PCHL diagnosis.

摘要

目的

本研究旨在探讨人口统计学变量、危险因素的有无以及新生儿普遍听力筛查(UNHS)结果是否可用于预测从筛查中转介的婴儿的永久性儿童听力损失(PCHL)。

设计

UNHS 数据库的回顾性分析。

研究样本

从澳大利亚昆士兰州 2007 年 1 月 1 日至 2016 年 12 月 31 日期间出生并参加 UNHS 的 613027 名婴儿的全州 UNHS 数据库中提取数据。本研究包括因一只或两只耳朵筛查未通过或筛查被跳过而从 UNHS 计划中转介进行诊断性听力学检查的 6735 名儿童。

结果

纳入逻辑回归模型的与 PCHL 具有显著正相关的因素包括:女性性别、非土著居民身份、PCHL 的家族史、颅面异常和与 PCHL 相关的综合征,以及双侧筛查转介结果。

结论

从 UNHS 计划中转介进行诊断评估的婴儿中,PCHL 的发生几率存在差异。当婴儿在新生儿听力筛查中被转介时,可以根据其性别、土著居民身份、已识别的危险因素和特定的筛查结果来预测先天性 PCHL 诊断的可能性。

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引用本文的文献

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Leading Risk Factors for Congenital Deafness in the Context of Universal Neonatal Screening: Our Observations in a Four-Year Retrospective Study.普遍新生儿筛查背景下先天性耳聋的主要危险因素:我们在一项四年回顾性研究中的观察结果
Int J Neonatal Screen. 2024 Jan 30;10(1):11. doi: 10.3390/ijns10010011.
2
Protocol and programme factors associated with referral and loss to follow-up from newborn hearing screening: a systematic review.与新生儿听力筛查的转诊和失访相关的方案和程序因素:系统评价。
BMC Pediatr. 2022 Aug 5;22(1):473. doi: 10.1186/s12887-022-03218-0.