人类微生物群与乳腺癌

HUMAN MICROBIOTA AND BREAST CANCER.

作者信息

Shvets Yu V, Lykhova O O, Chekhun V F

机构信息

NSC "Institute of Biology and Medicine" of Taras Shevchenko National University of Kyiv, Kyiv 01033, Ukraine.

R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv 03022, Ukraine.

出版信息

Exp Oncol. 2022 Aug;44(2):95-106. doi: 10.32471/exp-oncology.2312-8852.vol-44-no-2.17855.

DOI:10.32471/exp-oncology.2312-8852.vol-44-no-2.17855

PMID:35964650

Abstract

Breast cancer is the leading malignancy in women worldwide. To date, much is known about the molecular subtypes of these malignant neoplasms and the mechanisms of drug resistance. Significant success has been achieved in approaches to early diagnosis, which allows identifying the tumor process in the early stages of development. Recently, the study of the influence of the human body microbiota on cancer development and the effectiveness of treatment has become an actively developing field of research. This review presents an analysis of the literature data on this issue.

摘要

乳腺癌是全球女性中最主要的恶性肿瘤。迄今为止，人们对这些恶性肿瘤的分子亚型以及耐药机制已经有了很多了解。在早期诊断方法方面取得了重大成功，这使得能够在肿瘤发展的早期阶段识别肿瘤进程。最近，关于人体微生物群对癌症发展和治疗效果的影响的研究已成为一个积极发展的研究领域。本综述对关于这个问题的文献数据进行了分析。