Oppedal B R, Brandtzaeg P, Kemshead J T
Histopathology. 1987 Apr;11(4):363-74. doi: 10.1111/j.1365-2559.1987.tb02641.x.
A panel of monoclonal antibodies to neuroblastoma cells, leucocyte common antigen, vimentin and MHC class II antigens (HLA-DR) and a polyclonal antibody to epidermal keratin were used for immunohistochemistry on sections of ethanol fixed and paraffin embedded specimens from 40 undifferentiated small cell tumours and 10 neural crest neoplasms. With the exception of central nervous system neoplasms and two embryonal rhabdomyosarcomas, immunohistochemical examination discriminated between the neural crest neoplasms and the other small cell tumours. Moreover, the staining pattern of neoplastic cells and structures in the neural crest neoplasms obtained with antibodies to neuroblastoma cells seemed, in part, to reflect the degree of tumour differentiation.
使用一组针对神经母细胞瘤细胞、白细胞共同抗原、波形蛋白和MHC II类抗原（HLA - DR）的单克隆抗体，以及一种针对表皮角蛋白的多克隆抗体，对40例未分化小细胞肿瘤和10例神经嵴肿瘤的乙醇固定、石蜡包埋标本切片进行免疫组织化学检测。除中枢神经系统肿瘤和两例胚胎性横纹肌肉瘤外，免疫组织化学检查可区分神经嵴肿瘤和其他小细胞肿瘤。此外，用针对神经母细胞瘤细胞的抗体对神经嵴肿瘤中的肿瘤细胞和结构进行染色的模式，在一定程度上似乎反映了肿瘤的分化程度。
