Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
Gastroenterol Hepatol. 2023 Apr;46(4):274-281. doi: 10.1016/j.gastrohep.2022.07.005. Epub 2022 Aug 12.
Endoscopy units are considered to be at an increased risk of infection by SARS-CoV-2. Our aim is to assess the correlation between pre-endoscopic screening with reverse-transcription-polymerase-chain-reaction (RT-PCR) in asymptomatic individuals scheduled for elective endoscopy and the epidemiological data published by the local Health Administration.
Observational retrospective study collecting the results of our screening strategy spanning June/2020-June/2021, the effective potential growth (EPG), an index measuring the outbreak risk, and the 7 and 14-day cumulative incidence (CI). Indication, delay and the findings of the endoscopic examinations were registered for RT-PCR positive patients.
A total of 5808 tests were performed, yielding 125 positive results (2.15%). All positive tests occurred in weeks of high/very high risk (EPG>100) with the highest monthly rate being 9.36%, recorded in January/2021. A significant correlation (rho=0.796; p<0.001) between weekly positive rates and EPG was observed, and a significantly lower weekly number of positive tests was recorded when EPG<100. Planning the screening strategy one week ahead according to EPG>100 would have avoided up to 826 tests with only one positive result to account for. One hundred and thirteen individuals tested positive and 89 endoscopies were delayed. The most common findings were colon polyps, colorectal cancer and gastric metaplasia. Oncological diagnosis was delayed 50±3 days.
No positive RT-PCR test were registered out of high-risk periods. Epidemiological administrative data in the preceding two weeks showed a significant correlation with screening results and could be useful to plan pre-endoscopic screening and avoid unnecessary tests.
内窥镜检查单位被认为感染 SARS-CoV-2 的风险增加。我们的目的是评估在接受择期内窥镜检查的无症状个体中进行内窥镜检查前的逆转录聚合酶链反应（RT-PCR）筛查与当地卫生部门公布的流行病学数据之间的相关性。
这是一项观察性回顾性研究，收集了我们的筛查策略在 2020 年 6 月至 2021 年 6 月期间的结果，有效潜在增长率（EPG），一个衡量疫情风险的指数，以及 7 天和 14 天的累积发病率（CI）。对 RT-PCR 阳性患者的内镜检查的指征、延迟和结果进行了登记。
共进行了 5808 次检测，发现 125 次阳性结果（2.15%）。所有阳性检测均发生在高/极高风险（EPG>100）周，最高月发病率为 9.36%，记录在 2021 年 1 月。每周阳性率与 EPG 之间存在显著相关性（rho=0.796；p<0.001），当 EPG<100 时，每周阳性检测数量显著减少。根据 EPG>100 提前一周规划筛查策略，将避免多达 826 次检测，仅 1 次阳性结果。113 人检测呈阳性，89 例内镜检查延迟。最常见的发现是结肠息肉、结直肠癌和胃化生。肿瘤学诊断延迟了 50±3 天。
在高危期间未发现阳性 RT-PCR 检测结果。前两周的流行病学行政数据与筛查结果具有显著相关性，可用于规划内窥镜检查前的筛查并避免不必要的检测。
