Department of Ophtalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology and Chongqing Eye Institute, Chongqing 400000, China.
Contrast Media Mol Imaging. 2022 Jul 31;2022:6233232. doi: 10.1155/2022/6233232. eCollection 2022.
The aim of the present study was to investigate the effect of femtosecond laser small incision stromal lens extraction (SMILE), femtosecond laser-assisted excimer laser keratomileusis (FS-LASIK), and anterior elastic sublaminar laser keratomileusis (SBK) in myopic patients, and their effects on uncorrected visual acuity (UCVA) and tear film stability. 600 myopic patients admitted to our hospital from January 2020 to December 2021 were selected for the study and divided into SMILE group (200 patients, SMILE treatment), FS-LASIK group (200 patients, FS-LASIK treatment), and SBK group (200 patients, SBK treatment) according to the random number table method. Uncorrected visual acuity (UCVA), tear breakup time (BUT), tear secretion function test (Sit), and corneal higher-order image aberration global higher-order aberration (HOAS) were compared among the three groups. The UCVA values before operation, 2 weeks after operation, 1 month after operation, and 3 months after operation in the three groups were similar, and the BUT, Sit value, and HOAS of corneal higher-order image difference in the three groups were similar, and the differences were not statistically significant ( > 0.05). The BUT, Sit value, and HOAS of corneal higher-order image difference at 1 and 3 months after surgery in the SMILE group were higher than those in the FS-LASIK and SBK groups, and the differences were statistically significant ( < 0.05). SMILE, FS-LASIK, and SBK are effective in the treatment of myopia, which can effectively improve the uncorrected visual acuity and help the patients to recover their normal visual ability, but SMILE is more effective in tear film stability and corneal higher-order aberrations.
本研究旨在探讨飞秒激光小切口基质透镜提取术(SMILE)、飞秒激光辅助准分子激光角膜磨镶术(FS-LASIK)和前弹力层下激光角膜磨镶术(SBK)对近视患者的影响及其对未矫正视力(UCVA)和泪膜稳定性的影响。选择 2020 年 1 月至 2021 年 12 月期间我院收治的 600 例近视患者进行研究,按照随机数字表法分为 SMILE 组(200 例,SMILE 治疗)、FS-LASIK 组(200 例,FS-LASIK 治疗)和 SBK 组(200 例,SBK 治疗)。比较三组患者的未矫正视力(UCVA)、泪膜破裂时间(BUT)、泪液分泌功能测试(Sit)和角膜高阶像差全眼高阶像差(HOAS)。三组患者术前、术后 2 周、术后 1 个月、术后 3 个月的 UCVA 值比较,差异无统计学意义( > 0.05);三组患者角膜高阶像差差异的 BUT、Sit 值和 HOAS 比较,差异无统计学意义( > 0.05)。SMILE 组术后 1、3 个月的 BUT、Sit 值和角膜高阶像差差异的 HOAS 均高于 FS-LASIK 组和 SBK 组,差异有统计学意义( < 0.05)。SMILE、FS-LASIK 和 SBK 治疗近视均有效,可有效提高未矫正视力,帮助患者恢复正常视力,但 SMILE 对泪膜稳定性和角膜高阶像差的影响更明显。