Samarth Anagha, Budamakuntla Leelavathy, Shilpa Kanathur
Department of Dermatology, Blackpool Teaching Hospital NHS Foundation Trust, Bangalore, India.
Department of Dermatology, Bangalore Medical College, Bangalore, India.
J Cutan Aesthet Surg. 2022 Apr-Jun;15(2):131-134. doi: 10.4103/JCAS.JCAS_8_21.
Facial wounds, especially the ones lying perpendicular to the Lines of Langer, heal poorly. Several methods have been attempted to rectify this, but most of them do not target the underlying pathological process of scarring. Botulinum Toxin-A (BTA) has been successfully used for atrophic and hypertrophic scars.
This is a prospective study, where 30 patients who were operated for facial scar revision were divided into two equal groups: The first group was injected with BTA, but the second group was not. They were followed up for three months, and the results were analyzed.
Manchester scar scale (MSS) was used to assess the scars. In all the cases, the MSS score reduced after surgical correction, which further reduced after the injection of BTA in the first group of patients. The results are statistically significant ( < 0.01).
The BTA plays an important role in the treatment of scars after scar revision surgeries.
面部伤口，尤其是那些垂直于朗格线的伤口，愈合较差。人们尝试了多种方法来纠正这一情况，但大多数方法并未针对瘢痕形成的潜在病理过程。肉毒杆菌毒素A（BTA）已成功用于萎缩性和增生性瘢痕的治疗。
这是一项前瞻性研究，30例接受面部瘢痕修复手术的患者被平均分为两组：第一组注射BTA，第二组不注射。对两组患者进行了三个月的随访，并对结果进行了分析。
采用曼彻斯特瘢痕量表（MSS）评估瘢痕。在所有病例中，手术矫正后MSS评分降低，第一组患者注射BTA后评分进一步降低。结果具有统计学意义（<0.01）。
BTA在瘢痕修复手术后的瘢痕治疗中发挥着重要作用。
