Pagani J J, Kangarloo H, Gyepes M T, Feig S A, Falk P M
AJR Am J Roentgenol. 1979 Jun;132(6):883-90. doi: 10.2214/ajr.132.6.883.
Radiographically detectable complications in 35 children after bone marrow transplant are reviewed. These complications are most frequently due to infection, chemoradiotherapeutic toxicity, and graft versus host disease (a transplant rejection phenomenon peculiar to bone marrow transplant patients). The pulmonary complications within the first 2 months are secondary to a form of interstitial lung disease. Interstitial lung disease has a strong correlation with graft versus host disease. Extrapulmonary visceral complications include hepatosplenomegaly, nephromegaly, and hemorrhagic cystitis. These are due to graft versus host disease, radiation, and chemotherapeutic toxicities, respectively. Sinusitis, cerebral atrophy, and intracerebral hematomas are less frequent complications. Osteoporosis due to steroids is the single most important osseous complication.
回顾了35例儿童骨髓移植后影像学可检测到的并发症。这些并发症最常见的原因是感染、放化疗毒性以及移植物抗宿主病（一种骨髓移植患者特有的移植排斥现象）。移植后头2个月内的肺部并发症继发于一种间质性肺病。间质性肺病与移植物抗宿主病密切相关。肺外内脏并发症包括肝脾肿大、肾肿大和出血性膀胱炎。这些并发症分别由移植物抗宿主病、放疗和化疗毒性引起。鼻窦炎、脑萎缩和脑内血肿是较少见的并发症。类固醇引起的骨质疏松是最重要的骨并发症。
