Smith A G, Wright A L, Cabral J R
IARC Sci Publ. 1986(77):357-9.
The effect of hexachlorobenzene (HCB) on thyroid function in hamsters was explored and compared with that of 3-amino-1,2,4-triazole. Both chemicals caused thyroid enlargement but whereas 3-amino-1,2,4-triazole depressed serum thyroxine (T4) levels and elevated triiodothyronine (T3), HCB depressed T3 with little effect on T4.
研究了六氯苯(HCB)对仓鼠甲状腺功能的影响,并与3-氨基-1,2,4-三唑的影响进行了比较。两种化学物质都导致甲状腺肿大,但3-氨基-1,2,4-三唑会降低血清甲状腺素(T4)水平并升高三碘甲状腺原氨酸(T3),而HCB会降低T3,对T4影响不大。