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慢性透析儿童的主观全面营养评估[SGNA]——一项前瞻性观察研究

Subjective Global Nutritional Assessment [SGNA] in Children on Chronic Dialysis- A Prospective Observational Study.

作者信息

Iyengar Arpana, Ashok John M R, Vasudevan Anil

机构信息

Departments of Pediatric Nephrology and Biostatistics, St John's National Academy of Health Sciences, Bangalore, Karnataka, India.

出版信息

Indian J Nephrol. 2022 Jul-Aug;32(4):334-341. doi: 10.4103/ijn.ijn_340_21. Epub 2022 May 7.

Abstract

INTRODUCTION

Nutritional assessment in children undergoing chronic dialysis is challenging as no single objective reference tool is available. There is a need to explore the application of the subjective global nutritional assessment (SGNA) tool in these children. This study assessed the nutritional status of children on chronic dialysis using SGNA, evaluated the utility of SGNA parameters in the longitudinal assessment of nutrition, and compared the SGNA tool with other nutritional measures.

METHODS

Children 2-18 years of age on chronic dialysis for at least 1 month were prospectively studied over a period of 18 months with two follow-up visits at least 3 months apart. Malnutrition was diagnosed by SGNA (well-nourished, moderately, and severely malnourished), mid-arm circumference <5 centile for age and gender, and serum albumin <3.8 g/l at baseline and follow-up.

RESULTS

In 41 children on dialysis (age: 124.8 ± 32 months), 73% had moderate or severe malnutrition by SGNA. Height for age ( = 0.008), weight for height ( = 0.004), dietary intake ( = 0.025) functional capacity ( = 0.001), loss of subcutaneous fat (P < 0.001), and muscle wasting (P < 0.001) were significantly associated with the presence and severity of malnutrition. SGNA showed a poor agreement with MUAC and serum albumin. On follow-up, there was no significant change in the category of nutritional status ( = 0.63) and no individual SGNA parameter was associated with the presence or severity of malnutrition.

CONCLUSION

Two-thirds of the children on chronic dialysis were diagnosed with moderate to severe malnutrition by SGNA, while the majority remained in the same category of nutritional status on follow-up. Only half of the parameters used for assessment were strongly associated with the presence and severity of malnutrition. SGNA showed a poor agreement with objective nutritional measures and was not responsive in identifying a change in the nutritional status on follow-up.

摘要

引言

由于没有单一的客观参考工具,对接受慢性透析的儿童进行营养评估具有挑战性。有必要探索主观全面营养评估(SGNA)工具在这些儿童中的应用。本研究使用SGNA评估了接受慢性透析儿童的营养状况,评估了SGNA参数在营养纵向评估中的效用,并将SGNA工具与其他营养指标进行了比较。

方法

对年龄在2至18岁、接受慢性透析至少1个月的儿童进行了为期18个月的前瞻性研究,至少相隔3个月进行两次随访。通过SGNA(营养良好、中度和重度营养不良)、年龄和性别的上臂中部周长<第5百分位数以及基线和随访时血清白蛋白<3.8 g/l来诊断营养不良。

结果

在41名接受透析的儿童(年龄:124.8±32个月)中,73%通过SGNA诊断为中度或重度营养不良。年龄别身高(=0.008)、身高别体重(=0.004)、饮食摄入量(=0.025)、功能能力(=0.001)、皮下脂肪减少(P<0.001)和肌肉萎缩(P<0.001)与营养不良的存在和严重程度显著相关。SGNA与上臂中部周长和血清白蛋白的一致性较差。随访时,营养状况类别无显著变化(=0.63),且没有单个SGNA参数与营养不良的存在或严重程度相关。

结论

通过SGNA诊断,三分之二的慢性透析儿童患有中度至重度营养不良,而大多数儿童在随访时仍处于相同的营养状况类别。用于评估的参数中只有一半与营养不良的存在和严重程度密切相关。SGNA与客观营养指标的一致性较差,且在识别随访期间营养状况的变化方面没有反应。

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