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预测马来西亚终末期肾病患者截至2040年的发病率和患病率。

Forecasting the Incidence and Prevalence of Patients with End-Stage Renal Disease in Malaysia up to the Year 2040.

作者信息

Bujang Mohamad Adam, Adnan Tassha Hilda, Hashim Nadiah Hanis, Mohan Kirubashni, Kim Liong Ang, Ahmad Ghazali, Bak Leong Goh, Bavanandan Sunita, Haniff Jamaiyah

机构信息

National Clinical Research Centre, Kuala Lumpur, Malaysia.

Clinical Research Centre, Serdang Hospital, Kajang, Malaysia.

出版信息

Int J Nephrol. 2017;2017:2735296. doi: 10.1155/2017/2735296. Epub 2017 Feb 28.

Abstract

. The incidence of patients with end-stage renal disease (ESRD) requiring dialysis has been growing rapidly in Malaysia from 18 per million population (pmp) in 1993 to 231 pmp in 2013. . To forecast the incidence and prevalence of ESRD patients who will require dialysis treatment in Malaysia until 2040. . Univariate forecasting models using the number of new and current dialysis patients, by the Malaysian Dialysis and Transplant Registry from 1993 to 2013 were used. Four forecasting models were evaluated, and the model with the smallest error was selected for the prediction. . ARIMA (0, 2, 1) modeling with the lowest error was selected to predict both the incidence (RMSE = 135.50, MAPE = 2.85, and MAE = 87.71) and the prevalence (RMSE = 158.79, MAPE = 1.29, and MAE = 117.21) of dialysis patients. The estimated incidences of new dialysis patients in 2020 and 2040 are 10,208 and 19,418 cases, respectively, while the estimated prevalence is 51,269 and 106,249 cases. . The growth of ESRD patients on dialysis in Malaysia can be expected to continue at an alarming rate. Effective steps to address and curb further increase in new patients requiring dialysis are urgently needed, in order to mitigate the expected financial and health catastrophes associated with the projected increase of such patients.

摘要

在马来西亚,需要透析的终末期肾病(ESRD)患者的发病率一直在迅速增长,从1993年的每百万人口18例增至2013年的每百万人口231例。预测到2040年马来西亚需要透析治疗的ESRD患者的发病率和患病率。使用马来西亚透析与移植登记处1993年至2013年新透析患者和现有透析患者的数量进行单变量预测模型。评估了四种预测模型,并选择误差最小的模型进行预测。选择误差最低的ARIMA(0,2,1)模型来预测透析患者的发病率(均方根误差=135.50,平均绝对百分比误差=2.85,平均绝对误差=87.71)和患病率(均方根误差=158.79,平均绝对百分比误差=1.29,平均绝对误差=117.21)。2020年和2040年新透析患者的估计发病率分别为10208例和19418例,而估计患病率分别为51269例和106249例。预计马来西亚接受透析的ESRD患者数量将继续以惊人的速度增长。迫切需要采取有效措施来应对和遏制需要透析的新患者数量的进一步增加,以减轻与这类患者预计增加相关的预期财务和健康灾难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ada/5350290/e12439ba9f51/IJN2017-2735296.001.jpg

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