Donath Benitez Crisell Arely, Mattenberger-Cantú Estefanía, Salas-Flores Ricardo, Gómez-Morales Guillermo Baudelio, Mártinez-Diaz Paola Alejandra, Moreno-Treviño María Guadalupe, García-Tovar Laura Elvira, González-Salazar Francisco
Instituto Mexicano del Seguro Social, Ciudad Madero, Tamaulipas, Mexico.
Universidad de Monterrey, San Pedro Garza García, Nuevo León, México.
Glob Pediatr Health. 2022 Aug 8;9:2333794X221118017. doi: 10.1177/2333794X221118017. eCollection 2022.
The main objective of this work was to determine and update the causal agents' antibiotic sensitivity and resistance patterns on pediatric sepsis in a population of northeast Mexico. It is a cross-sectional study showing the results of blood cultures of pediatric patients with a presumptive diagnosis of sepsis were reviewed according to the SOFA criteria during 2020 in a public hospital in Mexico. A total of 207 blood cultures were performed and analyzed. The main isolated microorganisms were Staphylococcus, followed by Klebsiella and Escherichia. Several microorganisms showed 100% of sensitivity to different antibiotics or antifungals, some of them include Vancomycin, Voriconazole, Meropenem, Ciprofloxacin, and Cefotaxime. Bacteria of genre Staphylococcus showed its highest sensitivity rate to Tigecycline with 63.3%. Too Staphylococcus showed the highest resistance rate to Oxacillin with 50%. Although the patterns of sepsis-causing germs are similar to those previously reported, the development of new drugs with greater efficacy is the main contribution.
这项工作的主要目的是确定并更新墨西哥东北部人群中引起小儿败血症的病原体的抗生素敏感性和耐药模式。这是一项横断面研究，展示了2020年在墨西哥一家公立医院中，根据SOFA标准对疑似败血症的儿科患者的血培养结果进行的回顾。共进行并分析了207次血培养。主要分离出的微生物是葡萄球菌，其次是克雷伯菌和大肠杆菌。几种微生物对不同的抗生素或抗真菌药物表现出100%的敏感性，其中包括万古霉素、伏立康唑、美罗培南、环丙沙星和头孢噻肟。葡萄球菌属细菌对替加环素的敏感性最高，为63.3%。葡萄球菌对苯唑西林的耐药率也最高，为50%。尽管引起败血症的病菌模式与之前报道的相似，但开发更有效的新药是主要贡献。
