Artiles Medina Alberto, Gómez Dos Santos Victoria, Díez Nicolás Víctor, Hevia Palacios Vital, Ruiz Hernández Mercedes, Laso García Inés, Mata Alcaraz Marina, Galeano Álvarez Cristina, Jiménez Cidre Miguel Ángel, Arias Fúnez Fernando, Fernández Lucas Milagros, Burgos Revilla Francisco Javier
Department of Urology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain.
Department of Nephrology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Adv Urol. 2022 Aug 3;2022:9299397. doi: 10.1155/2022/9299397. eCollection 2022.
Transplantation surgery teams often have to face complex cases. In certain circumstances, such as occlusion of the iliac vessels or prior pelvic surgery, heterotopic kidney transplantation may not be feasible and orthotopic kidney transplantation (OKT) could be a good alternative. Kidney autotransplantation (KAT) has been described as a potential treatment for complex renovascular, ureteral, or neoplastic conditions. There are scarce data regarding the complications and outcomes of these procedures; therefore, we present our experience.
We retrospectively analysed the medical records of both 21 patients who had received OKT and 19 patients who underwent KAT between 1993 and 2020. We collected demographic features and data regarding surgical technique, complications, and graft outcomes. Kidney graft survival was calculated using Kaplan-Meier survival analysis.
Regarding OKT, in 15 (71.43%) cases, it was the first kidney transplantation. The most common indication was the unsuitable iliac region due to vascular abnormalities (57.14%). The early postoperative complication rate was high (66.67%), with 23.81% of Clavien grade 3b complications. During the follow-up period (mean 5.76 -SD 6.15- years), we detected 9 (42.85%) graft losses. At 1 year, the survival rate was 84.9%. Concerning KAT, the most frequent indication was ureteral pathology (52.63%), followed by vascular lesions (42.11%). The overall early complication rate was 42.11%. During the follow-up period (mean of 4.47 years), 4 (15.79%) graft losses were reported.
Although OKT and KAT have high complication rates, these techniques can be considered as two valuable approaches for complex cases, in the absence of other therapeutic options.
移植手术团队常常不得不面对复杂病例。在某些情况下,如髂血管闭塞或既往盆腔手术史,异位肾移植可能不可行,原位肾移植(OKT)可能是一个不错的选择。肾自体移植(KAT)已被描述为复杂肾血管、输尿管或肿瘤性疾病的一种潜在治疗方法。关于这些手术的并发症和结果的数据很少;因此,我们介绍我们的经验。
我们回顾性分析了1993年至2020年间接受OKT的21例患者和接受KAT的19例患者的病历。我们收集了人口统计学特征以及有关手术技术、并发症和移植物结果的数据。使用Kaplan-Meier生存分析计算肾移植物存活率。
关于OKT,15例(71.43%)为首次肾移植。最常见的适应证是由于血管异常导致髂区不适合(57.14%)。术后早期并发症发生率较高(66.67%),Clavien 3b级并发症发生率为23.81%。在随访期(平均5.76年 -标准差6.15年)内,我们检测到9例(42.85%)移植物丢失。1年时,存活率为84.9%。关于KAT,最常见的适应证是输尿管病变(52.63%),其次是血管病变(42.11%)。总体早期并发症发生率为42.11%。在随访期(平均4.47年)内,报告了4例(15.79%)移植物丢失。
尽管OKT和KAT的并发症发生率较高,但在没有其他治疗选择的情况下,这些技术可被视为复杂病例的两种有价值的方法。