Ren Linan, Gang Xiaokun, Yang Shuo, Sun Meixin, Wang Guixia
Department of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, China.
Department of Clinical Nutrition, The First Hospital of Jilin University, Changchun, China.
Front Neurol. 2022 Jul 29;13:911332. doi: 10.3389/fneur.2022.911332. eCollection 2022.
Shapiro's syndrome (SS) is characterized by spontaneous periodic hypothermia. It occurs to patients regardless of age or sex. To date, <60 cases have been reported worldwide. Current knowledge of the disease is limited to clinical feature since the pathogenesis and etiology are still controversial. In this review, the clinical characteristics, pathological mechanism, and possible etiology of the syndrome were reviewed to improve the clinical understanding of the disease.
夏皮罗综合征（SS）的特征是自发性周期性体温过低。该病可发生于任何年龄和性别的患者。迄今为止，全球报告的病例不足60例。由于发病机制和病因仍存在争议，目前对该疾病的了解仅限于临床特征。在本综述中，对该综合征的临床特征、病理机制和可能的病因进行了综述，以增进对该疾病的临床认识。
