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中国四川老年男性新发 HIV 感染的相关因素:一项病例对照研究。

The related factors of new HIV infection among older men in Sichuan, China: a case-control study.

机构信息

Sichuan Provincial Center for Disease Control and Prevention, Center for AIDS/STD Control and Prevention, Chengdu, Sichuan, China.

出版信息

Epidemiol Infect. 2022 Aug 15;150:e156. doi: 10.1017/S0950268822001352.

Abstract

Human immunodeficiency virus (HIV) has been widely prevalent among older men (aged ≥50 years old) in Sichuan Province. The study aimed to discover associated factors with the new HIV infection in older men, and provide a scientific basis for the prevention and control of acquired immunodeficiency syndrome (AIDS) in this group. A cross-sectional survey study of newly reported HIV/AIDS and general male residents aged 50 years and older was conducted between April and June 2019, with a resample of respondents to identify cases and controls, followed by a case-control study. Logistic regression was applied to analyse the association between the selected factors and new HIV infection among older men. At last, 242 cases and 968 controls were included. The results of multiple logistic regression suggested that many factors including living alone/concentrated (OR 1.56, 95% CI 1.20-2.04, = 0.001), have a history of migrant worker (OR 2.10, 95% CI 1.61-2.73, < 0.001), have commercial sexual behaviour (OR 1.71, 95% CI 1.32-2.22, < 0.001), married (OR 0.48, 95% CI 0.37-0.64, < 0.001), have a history of HIV antibody testing (OR 0.73, 95% CI 0.56-0.96, = 0.026), HIV-related knowledge (OR 0.55, 95% CI 0.42-0.72, < 0.001) were associated with new HIV infection among older men. The present study revealed some potential risky/protective factors altogether. The results highlighted the direction of HIV/AIDS prevention and control among older men, and it is a social issue that requires the joint participation of the whole society.

摘要

人类免疫缺陷病毒(HIV)在四川省老年男性(年龄≥50 岁)中广泛流行。本研究旨在探讨老年男性新发 HIV 感染的相关因素,为该人群艾滋病的预防和控制提供科学依据。2019 年 4 月至 6 月,采用横断面调查研究方法,对新报告的 HIV/AIDS 患者和一般男性居民进行了调查,对 50 岁及以上的受访者进行了再抽样,以确定病例和对照,然后进行病例对照研究。采用 logistic 回归分析选择因素与老年男性新发 HIV 感染的相关性。最终纳入 242 例病例和 968 例对照。多因素 logistic 回归结果显示,独居/聚居(OR 1.56,95%CI 1.20-2.04, = 0.001)、有流动人口史(OR 2.10,95%CI 1.61-2.73, < 0.001)、有商业性行为(OR 1.71,95%CI 1.32-2.22, < 0.001)、已婚(OR 0.48,95%CI 0.37-0.64, < 0.001)、有 HIV 抗体检测史(OR 0.73,95%CI 0.56-0.96, = 0.026)、HIV 相关知识(OR 0.55,95%CI 0.42-0.72, < 0.001)等因素与老年男性新发 HIV 感染有关。本研究揭示了一些潜在的危险因素和保护因素。结果强调了老年男性艾滋病预防和控制的方向,这是一个需要全社会共同参与的社会问题。

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