West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China; Sichuan Provincial Center for Disease Control and Prevention, Center for AIDS/STD Control and Prevention, Chengdu, Sichuan, China.
Sichuan Provincial Center for Disease Control and Prevention, Center for AIDS/STD Control and Prevention, Chengdu, Sichuan, China.
Int J Infect Dis. 2021 Apr;105:769-775. doi: 10.1016/j.ijid.2021.02.077. Epub 2021 Feb 19.
To describe epidemiological trends and spatial distributions of HIV/AIDS among older adults (aged ≥50) in Sichuan Province, China during 2008-19, and provide scientific reference for HIV/AIDS prevention, intervention and treatment.
Data on HIV/AIDS cases reported in 2008-19 was extracted from the Case Report System. The Cochran-Armitage trend test was used to determine epidemic trends. Spatial autocorrelation and space-time analysis were conducted with ArcGIS10.6 and ArcGIS Pro2.4, respectively.
A total of 77854 HIV/AIDS cases among older adults were included in the study. Newly reported cases increased from 320 in 2008 to 22189 in 2019, and the reported incidence rate (number of new reported cases/older adult population) rose from 0.001% to 0.077%. Infections through heterosexual transmission increased from 65.3% to 98.2% of total cases in older adults in this period. Spatial analysis at the county-level showed significant clustering throughout Sichuan, with the main hot spots concentrated in the southeast. Spatiotemporal analysis indicated that most of the southeastern counties/districts were Consecutive Hot Spots.
Older adults have become a key population in the HIV/AIDS epidemic in Sichuan; comprehensive prevention and intervention measures targeted to older adults are urgently needed to control the spread of HIV/AIDS.
描述 2008-19 年期间中国四川省老年(≥50 岁)艾滋病毒/艾滋病的流行病学趋势和空间分布,为艾滋病毒/艾滋病的预防、干预和治疗提供科学参考。
从病例报告系统中提取 2008-19 年报告的艾滋病毒/艾滋病病例数据。采用 Cochran-Armitage 趋势检验确定流行趋势。分别使用 ArcGIS10.6 和 ArcGIS Pro2.4 进行空间自相关和时空分析。
共纳入 77854 例老年艾滋病毒/艾滋病病例。新报告病例从 2008 年的 320 例增加到 2019 年的 22189 例,报告发病率(新报告病例数/老年人口)从 0.001%上升到 0.077%。在这一时期,老年艾滋病毒/艾滋病感染者中通过异性传播感染的比例从 65.3%上升到 98.2%。县级空间分析显示,四川全省存在显著的聚集性,主要热点集中在东南部。时空分析表明,东南部大部分县/区均为连续热点区。
老年群体已成为四川省艾滋病毒/艾滋病流行的重点人群;迫切需要针对老年群体的综合预防和干预措施,以控制艾滋病毒/艾滋病的传播。