Jacobi Christina
Klin Monbl Augenheilkd. 2022 Oct;239(10):1273-1286. doi: 10.1055/a-1892-6182. Epub 2022 Aug 15.
Dry Eye is one of the most common ocular diseases worldwide with an increasing number of patients. The pathogenesis of this disease is multifactorial and complex and the basis for diagnostic strategies and therapies. The current definition of dry eye disease as described in DEWS II includes inflammatory mechanisms at the ocular surface, a loss of homeostasis, hyperosmolarity of the tear film and neurosensory abnormalities. Subject symptom scores, a detailed patient history, certain diagnostic tools, and interdisciplinary interactions are necessary to enable an efficient, individualized and successful therapy. Important diagnostics include risk factor analysis, slit lamp examination, tear secretion tests, tearfilm stability tests, and tests for measuring the ocular surface inflammation.
干眼症是全球最常见的眼部疾病之一,患者数量不断增加。该疾病的发病机制是多因素且复杂的,是诊断策略和治疗的基础。《干眼综合征研究报告 II》中所描述的当前干眼症定义包括眼表的炎症机制、稳态失衡、泪膜高渗和神经感觉异常。患者症状评分、详细的病史、特定的诊断工具以及跨学科互动对于实现高效、个性化和成功的治疗是必要的。重要的诊断方法包括危险因素分析、裂隙灯检查、泪液分泌试验、泪膜稳定性试验以及测量眼表炎症的试验。